Causal inference analysis of the radiologic progression in the chronic obstructive pulmonary disease

There is limited evidence regarding the causal inference of emphysema and functional small airway disease in the subsequent progression of chronic obstructive pulmonary disease (COPD). Patients consisting of two independent cohorts diagnosed with COPD and underwent two serial chest CT scans were inc...

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Bibliographic Details
Published in:Scientific reports 2024-08, Vol.14 (1), p.17838-8, Article 17838
Main Authors: Im, Yunjoo, Lee, Kwonsang, Lee, Sang Min, Shin, Sun Hye, Choi, Yeonseok, Lee, Jae-Seung, Oh, Yeon Mok, Kim, Jonghoon, Oh, You Jin, Lee, Ho Yun, Park, Hye Yun
Format: Article
Language:English
Subjects:
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692/53/2422
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Aged
Allergic diseases
Chronic obstructive pulmonary disease
Computed tomography
Disease Progression
Emphysema
Female
Humanities and Social Sciences
Humans
Lung - diagnostic imaging
Lung - pathology
Lung diseases
Male
Middle Aged
multidisciplinary
Parametric response mapping
Pulmonary Disease, Chronic Obstructive - diagnostic imaging
Pulmonary Emphysema - diagnostic imaging
Respiratory tract diseases
Science
Science (multidisciplinary)
Small airway disease
Statistical analysis
Tomography, X-Ray Computed - methods
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Summary:There is limited evidence regarding the causal inference of emphysema and functional small airway disease in the subsequent progression of chronic obstructive pulmonary disease (COPD). Patients consisting of two independent cohorts diagnosed with COPD and underwent two serial chest CT scans were included. Total percent emphysema (PRM Emph ) and fSAD (PRM fSAD ) was quantified via PRM. To investigate the progression of emphysema, we divided COPD patients with PRM Emph  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-68560-y