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Postoperative Recovery Outcomes for Obese Patients Undergoing General Anesthesia: A Meta-Analysis of Randomized Controlled Trials

PurposeThis study was performed to assess the postoperative recovery outcomes in obese patients undergoing general anesthesia. MethodsThe eligible studies were identified from PubMed, EmBase, and the Cochrane library until December 2020. The standard mean differences (SMDs) with 95% confidence inter...

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Published in:Frontiers in surgery 2022-07, Vol.9, p.862632-862632
Main Authors: Hu, Zhen-Hua, Liu, Zhe, Zheng, Gai-Fang, Li, Zhan-Wen, Liu, Sheng-Qun
Format: Article
Language:English
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Summary:PurposeThis study was performed to assess the postoperative recovery outcomes in obese patients undergoing general anesthesia. MethodsThe eligible studies were identified from PubMed, EmBase, and the Cochrane library until December 2020. The standard mean differences (SMDs) with 95% confidence intervals (CIs) were used to calculate the role of desflurane, sevoflurane, and propofol on recovery outcomes, and the analyses using the random-effects model. ResultsEleven randomized controlled trials involving 713 obese patients undergoing general anesthesia were selected for final meta-analysis. We noted desflurane was associated with a shorter time to eye-opening than sevoflurane (SMD: -0.86; 95% CI, -1.43 to -0.28; P = 0.003). The use of desflurane with shorter time to extubation as compared with propofol (SMD: -1.13; 95% CI, -1.52 to -0.73; P 
ISSN:2296-875X
2296-875X
DOI:10.3389/fsurg.2022.862632