Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma

Urine autofluorescence at 295 nm is significantly higher in patients with malignant melanoma at each clinical stage compared to the healthy group. The largest difference is in the early-stages and without metastases. With increasing stage, the autofluorescence at 295 nm decreases. There is also a si...

Full description

Saved in:
Bibliographic Details
Published in:International journal of molecular sciences 2021-02, Vol.22 (4), p.1884
Main Authors: Birková, Anna, Valko-Rokytovská, Marcela, Hubková, Beáta, Zábavníková, Marianna, Mareková, Mária
Format: Article
Language:English
Subjects:
Adult
Aged
autofluorescence
Female
Fluorescence
Humans
Male
malignant melanoma
Melanoma - urine
Middle Aged
Neoplasm Staging
Spectrometry, Fluorescence
Tryptophan - urine
urine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673
cites cdi_FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673
container_end_page
container_issue 4
container_start_page 1884
container_title International journal of molecular sciences
container_volume 22
creator Birková, Anna
Valko-Rokytovská, Marcela
Hubková, Beáta
Zábavníková, Marianna
Mareková, Mária
description Urine autofluorescence at 295 nm is significantly higher in patients with malignant melanoma at each clinical stage compared to the healthy group. The largest difference is in the early-stages and without metastases. With increasing stage, the autofluorescence at 295 nm decreases. There is also a significant negative correlation between autofluorescence and Clark classification. Based on our results, it is assumed that the way malignant melanoma grows also affects urinary autofluorescence.
doi_str_mv 10.3390/ijms22041884
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_92bdd36327e1433b82afb04fb9ec7445</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_92bdd36327e1433b82afb04fb9ec7445</doaj_id><sourcerecordid>2498487742</sourcerecordid><originalsourceid>FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673</originalsourceid><addsrcrecordid>eNpVkUtP3DAURi0EKpR2x7rKkgUpfsWON5UQlIcEqsRj0ZVlxzdDRokdbA8V_74uQ9Gw8uvo-N77IXRA8HfGFD4ellOiFHPStnwL7RFOaY2xkNsb-130OaUlxpTRRn1Cu4wJ0Qqp9tDvuxyDX1RnMIN34DuoLOQ_AL66jy9zDvOj8fUtjCaDq87HVYiQulcu9NVDHDxUxrvqxozDwhufq5vC-jCZL2inN2OCr2_rPno4_3l_ellf_7q4Oj25rjve4FybUgjFlDfCcVO6YD1Q0lppObasacrBckGUI8o60_SksdT0IGnrnMBcSLaPrtZeF8xSz3GYTHzRwQz69SLEhTYxD90IWlHrHBOMSiCcMdsWlcW8two6yXlTXD_WrnllJ3ClzxzN-EH68cUPj3oRnrVUREoqiuDwTRDD0wpS1tNQxjWWkUBYJU25ankrJacFPVqjXQwpRejfvyFY_0tWbyZb8G-bpb3D_6NkfwG_rJ_w</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2498487742</pqid></control><display><type>article</type><title>Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma</title><source>PubMed Central Free</source><source>Publicly Available Content (ProQuest)</source><creator>Birková, Anna ; Valko-Rokytovská, Marcela ; Hubková, Beáta ; Zábavníková, Marianna ; Mareková, Mária</creator><creatorcontrib>Birková, Anna ; Valko-Rokytovská, Marcela ; Hubková, Beáta ; Zábavníková, Marianna ; Mareková, Mária</creatorcontrib><description>Urine autofluorescence at 295 nm is significantly higher in patients with malignant melanoma at each clinical stage compared to the healthy group. The largest difference is in the early-stages and without metastases. With increasing stage, the autofluorescence at 295 nm decreases. There is also a significant negative correlation between autofluorescence and Clark classification. Based on our results, it is assumed that the way malignant melanoma grows also affects urinary autofluorescence.</description><identifier>ISSN: 1422-0067</identifier><identifier>ISSN: 1661-6596</identifier><identifier>EISSN: 1422-0067</identifier><identifier>DOI: 10.3390/ijms22041884</identifier><identifier>PMID: 33668679</identifier><language>eng</language><publisher>Switzerland: MDPI</publisher><subject>Adult ; Aged ; autofluorescence ; Female ; Fluorescence ; Humans ; Male ; malignant melanoma ; Melanoma - urine ; Middle Aged ; Neoplasm Staging ; Spectrometry, Fluorescence ; Tryptophan - urine ; urine</subject><ispartof>International journal of molecular sciences, 2021-02, Vol.22 (4), p.1884</ispartof><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673</citedby><cites>FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673</cites><orcidid>0000-0002-5074-0125 ; 0000-0003-1614-460X ; 0000-0002-6291-4014</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917726/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917726/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33668679$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Birková, Anna</creatorcontrib><creatorcontrib>Valko-Rokytovská, Marcela</creatorcontrib><creatorcontrib>Hubková, Beáta</creatorcontrib><creatorcontrib>Zábavníková, Marianna</creatorcontrib><creatorcontrib>Mareková, Mária</creatorcontrib><title>Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma</title><title>International journal of molecular sciences</title><addtitle>Int J Mol Sci</addtitle><description>Urine autofluorescence at 295 nm is significantly higher in patients with malignant melanoma at each clinical stage compared to the healthy group. The largest difference is in the early-stages and without metastases. With increasing stage, the autofluorescence at 295 nm decreases. There is also a significant negative correlation between autofluorescence and Clark classification. Based on our results, it is assumed that the way malignant melanoma grows also affects urinary autofluorescence.</description><subject>Adult</subject><subject>Aged</subject><subject>autofluorescence</subject><subject>Female</subject><subject>Fluorescence</subject><subject>Humans</subject><subject>Male</subject><subject>malignant melanoma</subject><subject>Melanoma - urine</subject><subject>Middle Aged</subject><subject>Neoplasm Staging</subject><subject>Spectrometry, Fluorescence</subject><subject>Tryptophan - urine</subject><subject>urine</subject><issn>1422-0067</issn><issn>1661-6596</issn><issn>1422-0067</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkUtP3DAURi0EKpR2x7rKkgUpfsWON5UQlIcEqsRj0ZVlxzdDRokdbA8V_74uQ9Gw8uvo-N77IXRA8HfGFD4ellOiFHPStnwL7RFOaY2xkNsb-130OaUlxpTRRn1Cu4wJ0Qqp9tDvuxyDX1RnMIN34DuoLOQ_AL66jy9zDvOj8fUtjCaDq87HVYiQulcu9NVDHDxUxrvqxozDwhufq5vC-jCZL2inN2OCr2_rPno4_3l_ellf_7q4Oj25rjve4FybUgjFlDfCcVO6YD1Q0lppObasacrBckGUI8o60_SksdT0IGnrnMBcSLaPrtZeF8xSz3GYTHzRwQz69SLEhTYxD90IWlHrHBOMSiCcMdsWlcW8two6yXlTXD_WrnllJ3ClzxzN-EH68cUPj3oRnrVUREoqiuDwTRDD0wpS1tNQxjWWkUBYJU25ankrJacFPVqjXQwpRejfvyFY_0tWbyZb8G-bpb3D_6NkfwG_rJ_w</recordid><startdate>20210213</startdate><enddate>20210213</enddate><creator>Birková, Anna</creator><creator>Valko-Rokytovská, Marcela</creator><creator>Hubková, Beáta</creator><creator>Zábavníková, Marianna</creator><creator>Mareková, Mária</creator><general>MDPI</general><general>MDPI AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-5074-0125</orcidid><orcidid>https://orcid.org/0000-0003-1614-460X</orcidid><orcidid>https://orcid.org/0000-0002-6291-4014</orcidid></search><sort><creationdate>20210213</creationdate><title>Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma</title><author>Birková, Anna ; Valko-Rokytovská, Marcela ; Hubková, Beáta ; Zábavníková, Marianna ; Mareková, Mária</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Aged</topic><topic>autofluorescence</topic><topic>Female</topic><topic>Fluorescence</topic><topic>Humans</topic><topic>Male</topic><topic>malignant melanoma</topic><topic>Melanoma - urine</topic><topic>Middle Aged</topic><topic>Neoplasm Staging</topic><topic>Spectrometry, Fluorescence</topic><topic>Tryptophan - urine</topic><topic>urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Birková, Anna</creatorcontrib><creatorcontrib>Valko-Rokytovská, Marcela</creatorcontrib><creatorcontrib>Hubková, Beáta</creatorcontrib><creatorcontrib>Zábavníková, Marianna</creatorcontrib><creatorcontrib>Mareková, Mária</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>International journal of molecular sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Birková, Anna</au><au>Valko-Rokytovská, Marcela</au><au>Hubková, Beáta</au><au>Zábavníková, Marianna</au><au>Mareková, Mária</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma</atitle><jtitle>International journal of molecular sciences</jtitle><addtitle>Int J Mol Sci</addtitle><date>2021-02-13</date><risdate>2021</risdate><volume>22</volume><issue>4</issue><spage>1884</spage><pages>1884-</pages><issn>1422-0067</issn><issn>1661-6596</issn><eissn>1422-0067</eissn><abstract>Urine autofluorescence at 295 nm is significantly higher in patients with malignant melanoma at each clinical stage compared to the healthy group. The largest difference is in the early-stages and without metastases. With increasing stage, the autofluorescence at 295 nm decreases. There is also a significant negative correlation between autofluorescence and Clark classification. Based on our results, it is assumed that the way malignant melanoma grows also affects urinary autofluorescence.</abstract><cop>Switzerland</cop><pub>MDPI</pub><pmid>33668679</pmid><doi>10.3390/ijms22041884</doi><orcidid>https://orcid.org/0000-0002-5074-0125</orcidid><orcidid>https://orcid.org/0000-0003-1614-460X</orcidid><orcidid>https://orcid.org/0000-0002-6291-4014</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1422-0067
ispartof International journal of molecular sciences, 2021-02, Vol.22 (4), p.1884
issn 1422-0067
1661-6596
1422-0067
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_92bdd36327e1433b82afb04fb9ec7445
source PubMed Central Free; Publicly Available Content (ProQuest)
subjects Adult
Aged
autofluorescence
Female
Fluorescence
Humans
Male
malignant melanoma
Melanoma - urine
Middle Aged
Neoplasm Staging
Spectrometry, Fluorescence
Tryptophan - urine
urine
title Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T21%3A40%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Strong%20Dependence%20between%20Tryptophan-Related%20Fluorescence%20of%20Urine%20and%20Malignant%20Melanoma&rft.jtitle=International%20journal%20of%20molecular%20sciences&rft.au=Birkov%C3%A1,%20Anna&rft.date=2021-02-13&rft.volume=22&rft.issue=4&rft.spage=1884&rft.pages=1884-&rft.issn=1422-0067&rft.eissn=1422-0067&rft_id=info:doi/10.3390/ijms22041884&rft_dat=%3Cproquest_doaj_%3E2498487742%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c450t-a686202456d4a0413fe218b7b40b355e21b4619d19bda5f15b2afe728dd604673%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2498487742&rft_id=info:pmid/33668679&rfr_iscdi=true