Niacin increased glucose, insulin, and C-peptide levels in sedentary nondiabetic postmenopausal women

The current study examined the effects of niacin and a single bout of aerobic exercise on plasma glucose, insulin, and C-peptide in sedentary, nondiabetic postmenopausal women. As a crossover design, 17 participants underwent four different trials: rest during the no-niacin condition (R), exercise d...

Full description

Saved in:
Bibliographic Details
Published in:International journal of women's health 2014-01, Vol.6 (default), p.913-920
Main Authors: Koh, Yunsuk, Bidstrup, Heidi, Nichols, David L
Format: Article
Language:English
Subjects:
Aerobics
Blood pressure
Cardiovascular disease
Diabetes
Exercise intensity
Family medical history
Fitness equipment
Glucose
Health aspects
Heart rate
Hyperglycemia
Insulin resistance
Lipids
Lipoproteins
Metabolism
Niacin
Obesity
Original Research
Peptides
Physical fitness
Physiological aspects
Postmenopausal women
Risk factors
Sedentary behavior
Vitamin B
Womens health
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The current study examined the effects of niacin and a single bout of aerobic exercise on plasma glucose, insulin, and C-peptide in sedentary, nondiabetic postmenopausal women. As a crossover design, 17 participants underwent four different trials: rest during the no-niacin condition (R), exercise during the no-niacin condition (E), rest during the with-niacin condition (RN), and exercise during the with-niacin condition (EN). All participants took 1,000 mg/day of extended-release niacin for 4 weeks during the with-niacin conditions (RN and EN). The exercise treatment consisted of a single bout of treadmill walking at 60% heart rate reserve until 400 kcal were expended. Blood samples were collected at 24 hours after each trial and analyzed for changes in plasma glucose, insulin, and C-peptide. A two by two analysis of variance was used to examine the changes in dependent variables, and the Bonferroni adjustment was employed as the post hoc test. The level of statistical significance was set at P
ISSN:1179-1411
1179-1411
DOI:10.2147/IJWH.S69908