Laser-Inscribed Glass Microfluidic Device for Non-Mixing Flow of Miscible Solvents

In recent years, there has been significant research on integrated microfluidic devices. Microfluidics offer an advantageous platform for the parallel laminar flow of adjacent solvents of potential use in modern chemistry and biology. To reach that aim, we worked towards the realization of a buried...

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Bibliographic Details
Published in:Micromachines (Basel) 2018-12, Vol.10 (1), p.23
Main Authors: Italia, Valeria, Giakoumaki, Argyro N, Bonfadini, Silvio, Bharadwaj, Vibhav, Le Phu, Thien, Eaton, Shane M, Ramponi, Roberta, Bergamini, Giacomo, Lanzani, Guglielmo, Criante, Luigino
Format: Article
Language:English
Subjects:
Analytical chemistry
Chemical etching
Chemical reactions
Configurations
diffusion
Diffusion rate
Etching
Ethanol
femtosecond laser
Interfaces
lab-on-a-chip
Laminar flow
Laminar mixing
laser micromachining
Lasers
Mass transfer
Microfluidic devices
Microfluidics
Optimization
optofluidics
Organic chemistry
Solvents
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Summary:In recent years, there has been significant research on integrated microfluidic devices. Microfluidics offer an advantageous platform for the parallel laminar flow of adjacent solvents of potential use in modern chemistry and biology. To reach that aim, we worked towards the realization of a buried microfluidic Lab-on-a-Chip which enables the separation of the two components by exploiting the non-mixing properties of laminar flow. To fabricate the aforementioned chip, we employed a femtosecond laser irradiation technique followed by chemical etching. To optimize the configuration of the chip, several geometrical and structural parameters were taken into account. The diffusive mass transfer between the two fluids was estimated and the optimal chip configuration for low diffusion rate of the components was defined.
ISSN:2072-666X
2072-666X
DOI:10.3390/mi10010023