Effects of the Usage of l-Cysteine (l-Cys) on Human Health

This review summarizes recent knowledge about the use of the amino acid l-Cysteine (l-Cys) through diet, nutritional supplements or drugs with the aim to improve human health or treat certain diseases. Three databases (PubMed, Scopus, and Web of Science) and different keywords have been used to crea...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2018-03, Vol.23 (3), p.575
Main Authors: Clemente Plaza, Noelia, Reig García-Galbis, Manuel, Martínez-Espinosa, Rosa María
Format: Article
Language:English
Subjects:
">l-cysteine
Alopecia - diet therapy
Alopecia - metabolism
Bibliometrics
biological medicine
Clinical trials
Clinical Trials as Topic
Cysteine
Cysteine - administration & dosage
Diabetes Mellitus, Type 2 - diet therapy
Diabetes Mellitus, Type 2 - metabolism
Diet - methods
Dietary Supplements
Documents
Drugs
Feeding Behavior
Functional foods & nutraceuticals
Health
Humans
Medical research
nutraceutical
nutritional therapy
Porphyria, Erythropoietic - diet therapy
Porphyria, Erythropoietic - metabolism
Precision Medicine
Review
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Summary:This review summarizes recent knowledge about the use of the amino acid l-Cysteine (l-Cys) through diet, nutritional supplements or drugs with the aim to improve human health or treat certain diseases. Three databases (PubMed, Scopus, and Web of Science) and different keywords have been used to create a database of documents published between 1950 and 2017 in scientific journals in English or Spanish. A total of 60,885 primary publications were ultimately selected to compile accurate information about the use of l-Cys in medicine and nutritional therapies and to identify the reported benefits of l-Cys on human health. The number of publications about the use of l-Cys for these purposes has increased significantly during the last two decades. This increase seems to be closely related to the rise of nutraceutical industries and personalized medicine. The main evidence reporting benefits of l-Cys usage is summarized. However, the lack of accurate information and studies based on clinical trials hampers consensus among authors. Thus, the debate about the role and effectiveness of supplements/drugs containing l-Cys is still open.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules23030575