Ultrasound-assisted production and optimization of mini-emulsions in a microfluidic chip in continuous-flow

[Display omitted] •Fast generation of W/O and O/W emulsions with low-reagent consumption.•Images show the initial formation of the emulsion by cavitation bubbles.•Emulsion droplet diameter is independent of ultrasound power.•Emulsions with different HLB values were formed in continuous flow.•Submicr...

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Bibliographic Details
Published in:Ultrasonics sonochemistry 2021-06, Vol.74, p.105556-105556, Article 105556
Main Authors: Nieves, Erick, Vite, Giselle, Kozina, Anna, Olguin, Luis F.
Format: Article
Language:English
Subjects:
Dimethylpolysiloxanes - chemistry
Emulsions
High-power ultrasound
Hydrodynamics
In-line emulsification
Lab-On-A-Chip Devices
Microfluidics
Nylons - chemistry
Oils - chemistry
Original
Polymeric particles synthesis
Surface-Active Agents - chemistry
Ultrasonic emulsification
Ultrasonic Waves
W/o and o/w emulsions
Water - chemistry
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Description
Summary:[Display omitted] •Fast generation of W/O and O/W emulsions with low-reagent consumption.•Images show the initial formation of the emulsion by cavitation bubbles.•Emulsion droplet diameter is independent of ultrasound power.•Emulsions with different HLB values were formed in continuous flow.•Submicron polymeric particles with low dispersity were synthesized from miniemulsions. The use of ultrasound to generate mini-emulsions (50 nm to 1 μm in diameter) and nanoemulsions (mean droplet diameter 
ISSN:1350-4177
1873-2828
DOI:10.1016/j.ultsonch.2021.105556