Factors Affecting Final Surgical Outcome of Combined Trabeculotomy-Trabeculectomy in Primary Congenital Glaucoma

To evaluate different pre-operative variables on the success of combined trabeculotomy-trabeculectomy (CTT) surgery in patients with primary congenital glaucoma (PCG) to predict those at higher risk for surgical failure and for proper parent counseling. Sixty-three eyes of patients with PCG were tre...

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Bibliographic Details
Published in:Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2022-01, Vol.16, p.43-49
Main Authors: Khairy, Marwa A, Kenawy, Said, Fawzi, Khaled Mohamed, Al-Nashar, Haitham Y
Format: Article
Language:English
Subjects:
Analysis
Biological products
buphthalmous
Care and treatment
Collagen
Congenital diseases
Cornea
Edema
Evaluation
Family medical history
Genetic disorders
Glaucoma
Glaucoma in children
kaplan–meier survival analysis
Original Research
Patients
Surgery
surgical failure
Surgical outcomes
Survival analysis
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Summary:To evaluate different pre-operative variables on the success of combined trabeculotomy-trabeculectomy (CTT) surgery in patients with primary congenital glaucoma (PCG) to predict those at higher risk for surgical failure and for proper parent counseling. Sixty-three eyes of patients with PCG were treated either with CTT without augmentation, or CTT augmented with mitomycin-C (0.2 mg/mL) in both subconjunctival space and under scleral flap for 3 minutes, or with CTT augmented with a collagen implant under both the scleral flap and the conjunctiva. Cases showed surgical failure was reported and evaluated in relation to different pre-operative variables. Complete success (IOP ≤21 mmHg) was achieved in 52 cases (82.5%). Cumulative success probability was calculated using Kaplan-Meier survival analysis, proving that higher pre-operative intraocular pressure (IOP) was associated with higher failure rates (28.6% for pre-operative IOP ≥30 mmHg versus 4.8% for IOP
ISSN:1177-5467
1177-5483
1177-5483
DOI:10.2147/OPTH.S344479