Successful treatment of late Salmonella infections in total hip replacement - report of two cases

Salmonella species can be rarely isolated from periprosthetic joint infections, however when present, are usually part of a severe septic clinical picture. Two patients presented with late infected hip replacements to our institution. The first patient with multiple comorbidities had a confirmed Sal...

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Bibliographic Details
Published in:BMC infectious diseases 2010-06, Vol.10 (1), p.160-160, Article 160
Main Authors: Tóth, Kálmán, Janositz, Gábor, Kovács, Gyula, Sisák, Krisztián, Rudner, Ervin
Format: Article
Language:English
Subjects:
Aged
Anti-Bacterial Agents - therapeutic use
Arthroplasty, Replacement, Hip
Case Report
Case studies
Causes of
Ciprofloxacin
Ciprofloxacin - therapeutic use
Diagnosis
Dosage and administration
Drug therapy
Humans
Male
Middle Aged
Prosthesis-Related Infections - drug therapy
Prosthesis-Related Infections - microbiology
Prosthesis-Related Infections - surgery
Salmonella
Salmonella arizonae - isolation & purification
Salmonella enteritidis - isolation & purification
Salmonella Infections - diagnosis
Salmonella Infections - drug therapy
Salmonella Infections - surgery
Salmonellosis
Treatment Outcome
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Summary:Salmonella species can be rarely isolated from periprosthetic joint infections, however when present, are usually part of a severe septic clinical picture. Two patients presented with late infected hip replacements to our institution. The first patient with multiple comorbidities had a confirmed Salmonella Enteridis infection with an abscess in the groin, with loosening of both components. He underwent a successful one stage cemented revision hip replacement, followed by 6 weeks of antibiotic therapy (ciprofloxacin). He had no recurrence or complications. The second patient was admitted in a septic condition with ARDS to the Intensive Care Unit 7 years following an uncemented total hip replacement. From an ultrasound guided hip aspirate Salmonella cholerae-suis was isolated. He underwent a successful a two-stage revision hip replacement. Successful treatment of such potentially life threatening infections is achievable using modern orthopaedic techniques and close collaboration with the infectious diseases specialists.
ISSN:1471-2334
1471-2334
DOI:10.1186/1471-2334-10-160