Potential Microbiological Risk Factors Associated With Periodontitis and Periodontal Health Disparities

Periodontitis disproportionately affects different racial and ethnic populations. In this study, we used qPCR to determine and compare oral microbial profiles in dental plaque samples from 191 periodontitis patients of different ethnic/racial backgrounds. We also obtained the periodontal parameters...

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Bibliographic Details
Published in:Frontiers in cellular and infection microbiology 2021-11, Vol.11, p.789919-789919
Main Authors: Wang, Bing-Yan, Lu, Tom, Cai, Qiuyin, Ho, Meng-Hsuan, Sheng, Sally, Meng, Hsiu-Wan, Arsto, Laura, Hong, Jianming, Xie, Hua
Format: Article
Language:English
Subjects:
Cellular and Infection Microbiology
Humans
microbial profiles
periodontitis
Periodontitis - epidemiology
Porphyromonas gingivalis
Porphyromonas gingivalis - genetics
racial and ethnic groups
Retrospective Studies
Risk Factors
Streptococcus cristatus
Virulence
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Summary:Periodontitis disproportionately affects different racial and ethnic populations. In this study, we used qPCR to determine and compare oral microbial profiles in dental plaque samples from 191 periodontitis patients of different ethnic/racial backgrounds. We also obtained the periodontal parameters of these patients retrospectively using axiUm and performed statistical analysis using SAS 9.4. We found that in this patient cohort, neighborhood median incomes were significantly higher among Caucasians Americans (CAs) than among African Americans (AAs) and Hispanic Americans (HAs). Levels of total bacteria and , a keystone periodontal pathogen, were not evenly distributed among the three groups. We confirmed our previous findings that reduces virulence potential and likely serves as a beneficial bacterium. We also showed the ratio of to to be significantly higher in CAs than in HAs and AAs. Our results suggest that higher levels of and lower ratios of to may contribute to periodontal health disparities.
ISSN:2235-2988
2235-2988
DOI:10.3389/fcimb.2021.789919