Effect of an aqueous 4% titanium tetrafluoride solution on preventing caries in orthodontic patients: a controlled clinical trial

Titanium tetrafluoride (TiF4) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO2) acid-resistant coat. This study sought to verify the hypothesis that a single application of 4% TiF4 increases the resistance of en...

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Bibliographic Details
Published in:Dental press journal of orthodontics 2023, Vol.28 (1), p.e2321304-e2321304
Main Authors: Chevitarese, Ana Beatriz, Leite, Karla Lorene de França, Dutra, Paulo Bechara, Pithon, Matheus Melo, Faria, Lucianne Cople Maia, Ruellas, Antônio Carlos de Oliveira
Format: Article
Language:English
Subjects:
Biofilms
Clinical trials
Dental caries
Dental Caries - prevention & control
Dental Caries Susceptibility
Dental Enamel
DENTISTRY, ORAL SURGERY & MEDICINE
Disease prevention
Enamel
Fluoridation
Fluorides
Fluorides - pharmacology
Humans
Laboratories
Original
Orthodontics
Patients
Potash
Potassium
Retention
Teeth
Titanium
Titanium - pharmacology
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Summary:Titanium tetrafluoride (TiF4) is a fluoride compound that, when is applied over enamel, promotes a protection against demineralization through a titanium dioxide (TiO2) acid-resistant coat. This study sought to verify the hypothesis that a single application of 4% TiF4 increases the resistance of enamel to dental demineralization in orthodontic patients. This controlled clinical trial followed CONSORT guidelines and investigated the prevention of enamel demineralization, fluoride retention, and the presence of a Ti layer after TiF4 application on banded teeth exposed to clinical cariogenic biofilm. Forty premolars were divided into a control group (CG; n = 20) and a test group (TG; n = 20). Teeth from both groups received prophylaxis and orthodontic bands with a cariogenic locus. In the TG, all teeth additionally underwent aqueous 4% TiF4 solution application after prophylaxis before being banded. After one month, teeth from both groups were extracted and prepared to assess the microhardness, fluoride retention, and evaluation of the Ti coating over the enamel surface. All data were analyzed with a paired Student's t-test (p
ISSN:2176-9451
2177-6709
2177-6709
DOI:10.1590/2177-6709.28.1.e2321304.oar