Cryptosporidium spp. infection in Iranian children and immunosuppressive patients: A systematic review and meta-analysis

Cryptosporidiosis is an important cause of diarrhea in children and immunosuppressive patients. The current study was intended to evaluate the prevalence rate of infection and clarify the epidemiological characteristics of the infection in both children and immunosuppressive patients in Iran. Five E...

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Bibliographic Details
Published in:Caspian journal of internal medicine 2018, Vol.9 (2), p.106-115
Main Authors: Kalantari, Narges, Ghaffari, Salman, Bayani, Masomeh
Format: Article
Language:English
Subjects:
Children
Cryptosporidiosis
Cryptosporidium spp
Immunosuppressive patients
Iran
Prevalence
Review
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Summary:Cryptosporidiosis is an important cause of diarrhea in children and immunosuppressive patients. The current study was intended to evaluate the prevalence rate of infection and clarify the epidemiological characteristics of the infection in both children and immunosuppressive patients in Iran. Five English electronic databases including PubMed, Google Scholar, Science Direct, Scopus and Cochrane, and two Persian language databases Magiran and Scientific Information Database were searched. Additionally, reports from the Iranian congresses of parasitology and graduate student thesis dissertations were assessed manually. Out of 1856 studies from the literature search, our search resulted in a total of 27 articles published from 1991 to 2016. These include 14 reports on cryptosporidiosis in children and 13 papers regarding immunosuppressive patients. 8520 children and 2015 immunosuppressed cases were evaluated. Oocysts of were found in 3.8% and 8% children cases and immunosuppressed patients, respectively. There was a relatively high variation in the prevalence estimates among different studies, and the Q statistics was high among articles regarding children (p
ISSN:2008-6164
2008-6172
DOI:10.22088/cjim.9.2.106