Secondary Metabolites from Polar Organisms

Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms,...

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Bibliographic Details
Published in:Marine drugs 2017-02, Vol.15 (3), p.28
Main Authors: Tian, Yuan, Li, Yan-Ling, Zhao, Feng-Chun
Format: Article
Language:English
Subjects:
Animals
Antarctic Regions
Aquatic Organisms - chemistry
Arctic Regions
Biocompatibility
biological activity
Biological Products - chemistry
Biological Products - metabolism
Biosynthesis
chemical synthesis
Drugs
Humans
Marine Biology - methods
Marine microorganisms
Metabolites
Microorganisms
Mosses
Natural products
Polar regions
Review
secondary metabolism
Secondary metabolites
structure elucidation
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Summary:Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms, lichen, moss and marine faunas. The structures of the new compounds and details of the source organism, along with any relevant biological activities are presented. Where reported, synthetic and biosynthetic studies on the polar metabolites have also been included.
ISSN:1660-3397
1660-3397
DOI:10.3390/md15030028