Single nucleotide polymorphism typing of Bacillus anthracis from Sverdlovsk tissue

A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient's B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that def...

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Bibliographic Details
Published in:Emerging infectious diseases 2008-04, Vol.14 (4), p.653-656
Main Authors: Okinaka, Richard T, Henrie, Melinda, Hill, Karen K, Lowery, Kristin S, Van Ert, Matthew, Pearson, Talima, Schupp, James, Kenefic, Leo, Beaudry, Jodi, Hofstadler, Steven A, Jackson, Paul J, Keim, Paul
Format: Article
Language:English
Subjects:
anthrax
Anthrax - epidemiology
Anthrax - microbiology
Antigens, Bacterial - genetics
Bacillus anthracis
Bacillus anthracis - classification
Bacillus anthracis - genetics
Bacterial Proteins - genetics
Bacterial Toxins - genetics
canSNP
Dispatch
DNA, Bacterial - chemistry
Genetic aspects
Genotype
Health aspects
Humans
Immunology
Infectious Diseases
Inhalation Exposure
pagA
Phylogeny
Polymorphism, Single Nucleotide
Russia - epidemiology
Single nucleotide polymorphisms
Sverdlovsk
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Summary:A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient's B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1404.070984