Effect of mineral excipients on processing traditional Chinese medicines: an insight into the components, pharmacodynamics and mechanism

Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own hard texture, impurities or toxicity. As an important part of solid excipients, mineral exci...

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Bibliographic Details
Published in:Chinese medicine 2021-12, Vol.16 (1), p.143-143, Article 143
Main Authors: Liu, Yan, Li, Xiaojie, Chen, Cai, Leng, Aijing, Qu, Jialin
Format: Article
Language:English
Subjects:
Amino acids
Components
Drugs
Impurities
Lectins
Lime
Mechanism
Medical research
Medicine, Chinese
Mineral excipients
Minerals
Natural products
Pharmacodynamics
Processing
Proteins
Review
Toxicity
Traditional Chinese medicine
Traditional Chinese medicine (TCM)
Vinegar
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Summary:Traditional Chinese medicines are an important class of natural products mainly derives from animals, plants and minerals, most of which need to be improved and processed before clinical use due to their own hard texture, impurities or toxicity. As an important part of solid excipients, mineral excipients that contain some metal elements play indispensable and unique roles in the pretreatment process of traditional Chinese medicine. However, deficiency of holistic understanding of the effect of mineral excipients hinders their application and development. This article reviews several mineral excipients including alumen, talci pulvis, soil, soda lime, halloysitum rubrum and cinnabaris systemically. Their processing significance on traditional Chinese medicines were revealed from components, pharmacodynamics and mechanism aspects. Furthermore, prospect and problems including processing technologies, quality standards of mineral excipients and processing mechanism were put forward. This review supply comprehensive information for better and scientific usage of mineral excipients in processing traditional Chinese medicines.
ISSN:1749-8546
1749-8546
DOI:10.1186/s13020-021-00554-8