mcr-1 and blaKPC-3 in Escherichia coli Sequence Type 744 after Meropenem and Colistin Therapy, Portugal

Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to...

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Bibliographic Details
Published in:Emerging infectious diseases 2017-08, Vol.23 (8), p.1419-1421
Main Authors: Tacão, Marta, Tavares, Rafael Dos Santos, Teixeira, Pedro, Roxo, Inês, Ramalheira, Elmano, Ferreira, Sónia, Henriques, Isabel
Format: Article
Language:English
Subjects:
and
antibacterial
antimicrobial
co-resistance
fluconazole
Gene, carbapenem, meropenem, colistin, polymixin
linezolid
Research Letter
Sequence Type 744 after Meropenem and Colistin Therapy, Portugal
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Summary:Escherichia coli Ec36 was recovered from a patient in Portugal after treatment with meropenem and colistin. Besides an IncF plasmid with Tn1441d-blaKPC-3, already reported in clinical strains in this country, E. coli Ec36 co-harbored an IncX4::mcr-1 gene. Results highlight emerging co-resistance to carbapenems and polymyxins after therapy with drugs from both classes.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2308.170162