Simulated weightbearing computed tomography for verification of radiographic staging of varus ankle osteoarthritis: a cross-sectional study

• Published in: BMC musculoskeletal disorders 2021-08, Vol.22 (1), p.1-737, Article 737
• Main Authors: Tomiwa, Kiyonori, Tanaka, Yasuhito, Kurokawa, Hiroaki, Kadono, Kunihiko, Taniguchi, Akira, Maliwankul, Korakot
• Format: Article
• Language: English
• Subjects: Ankle; Ankle osteoarthritis; Arthritis; Computed tomography; Cross-sectional studies; CT imaging; Development and progression; Diagnosis; Knee; Medical imaging; Musculoskeletal diseases; Osteoarthritis; Patients; Radiography; Stage classification; Tibia; varus; Weight-bearing computed tomography
• ISSN: 1471-2474; 1471-2474
• DOI: 10.1186/s12891-021-04618-6

Background Varus ankle osteoarthritis is classified using only weightbearing anteroposterior ankle radiographs; however, sagittal ankle alignment may also affect the position and extent of joint space obliteration. We hypothesized that the sagittal alignment of the ankle may also affect the position and extent of joint space obliteration visible on the coronal section; therefore, we identified the sites of joint space obliteration in patients with stage 3 varus ankle osteoarthritis for comparison with the sites observed on simulated weightbearing computed tomography and investigated the effects of anterior and posterior ankle subluxation. Methods Simulated weightbearing computed tomography scans of 83 ft with varus ankle osteoarthritis (26 stage 3a, 57 stage 3b) were performed to check for joint space obliteration in the ankle. Further classification as exhibiting either anterior, posterior, or no subluxation on weightbearing lateral radiographs was performed. Results Anterior, posterior, and no subluxation was seen in 5, 9, and 12 ankles among the 26 classified as stage 3a, respectively, and in 22, 12, and 23 ankles among the 57 classified as stage 3b, respectively. The mean tibial lateral surface angle on weightbearing lateral radiographs in stage 3a ankles was 75.6, 83.3, and 80.3 degrees in the anterior, posterior, and no subluxation groups, respectively; and 75.5, 86.6, and 82.7 degrees in stage 3b ankles (p < .05). In stage 3b ankles, widespread joint space obliteration was observed at the anterior distal articular surface of the tibia in all 22 ankles with anterior subluxation and at the posterior distal articular surface of the tibia in all 12 ankles with posterior subluxation. Conclusions Simulated weightbearing computed tomography revealed joint space obliteration at the anterior distal articular surface of the tibia in stage 3b ankles with anterior subluxation and at the posterior side in stage 3a and 3b ankles with posterior subluxation. In some patients with stage 3 varus ankle osteoarthritis, the obliteration of the joint space is difficult to evaluate accurately using only weightbearing anteroposterior radiographs; weightbearing lateral radiographs should also be performed. Keywords: Ankle osteoarthritis, varus, Stage classification, Weight-bearing computed tomography