Is There a Relationship between Adverse Pregnancy Outcomes and Future Development of Atherosclerosis?

Cardiovascular disease is one of the main death causes globally. Effective cardiovascular risk management requires a thorough understanding of the mechanisms underlying the disorder. Establishing early markers of the disease allows a timely intervention and prevention of further atherosclerosis deve...

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Bibliographic Details
Published in:Biomedicines 2023-08, Vol.11 (9), p.2430
Main Authors: Poznyak, Anastasia V, Khotina, Victoria A, Zhigmitova, Elena B, Sukhorukov, Vasily N, Postnov, Anton Y, Orekhov, Alexander N
Format: Article
Language:English
Subjects:
Analysis
Arteriosclerosis
Atherosclerosis
Biomarkers
Blood pressure
Blood vessels
Cardiovascular disease
Cardiovascular diseases
cardiovascular risk factors
Cardiovascular system
Cholesterol
Cytokines
Development and progression
Diabetes mellitus
Females
Fetuses
gestation
Gestational diabetes
Growth factors
Hypertension
Immune system
Kidneys
Medical research
Medicine, Experimental
Metabolism
MicroRNAs
Physiology
Placenta
Preeclampsia
pregnancy
Pregnancy complications
Pregnant women
Premature birth
Prevention
Review
Risk factors
Stillbirth
Triglycerides
Womens health
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Summary:Cardiovascular disease is one of the main death causes globally. Effective cardiovascular risk management requires a thorough understanding of the mechanisms underlying the disorder. Establishing early markers of the disease allows a timely intervention and prevention of further atherosclerosis development. Multiple studies confirm the correlation between pregnancy disorders and cardiovascular disease in the postpartum period. Moreover, over 30% of women experience adverse pregnancy outcomes. Thus, the examination of the links between these conditions and atherosclerotic cardiovascular disease may help to identify gender-specific risk factors. In this review, we will explore the association between several adverse pregnancy outcome conditions and atherosclerosis. The current analysis is based on the data from several recent studies on the mechanisms behind gestational diabetes, hypertensive disorders of pregnancy, miscarriages, and stillbirths and their implications for the female cardiovascular system.
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines11092430