Impact of co-amoxicillin-resistant Escherichia coli and Pseudomonas aeruginosa on the rate of infectious complications in paediatric complicated appendicitis

Choice of antibiotics for complicated appendicitis should address local antibiotic resistance patterns. As our local data showed a less than 15% resistance of Escherichia coli to co-amoxicillin (amoxicillin + clavulanic acid), we opted for this antibiotic in 2013. Subsequently, the increasing preval...

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Bibliographic Details
Published in:Swiss medical weekly 2019-04, Vol.149 (1718), p.w20055-w20055
Main Authors: Andrey, Véronique, Crisinel, Pierre-Alex, Prod'hom, Guy, Croxatto, Antony, Joseph, Jean-Marc
Format: Article
Language:English
Subjects:
Amoxicillin - pharmacology
Anti-Bacterial Agents - pharmacology
antibiotic therapy
Appendectomy - adverse effects
Appendicitis - drug therapy
Appendicitis - microbiology
Appendicitis - surgery
Child
Child, Preschool
complicated appendicitis
Drug Resistance, Bacterial
Escherichia coli - drug effects
Escherichia coli - isolation & purification
Female
Humans
Male
Microbial Sensitivity Tests
Peritoneal Cavity - microbiology
Peritonitis - epidemiology
Peritonitis - microbiology
Postoperative Complications - epidemiology
Postoperative Complications - microbiology
Pseudomonas aeruginosa - drug effects
Pseudomonas aeruginosa - isolation & purification
resistant
Retrospective Studies
Risk Assessment
Risk Factors
Citations: Items that cite this one
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Summary:Choice of antibiotics for complicated appendicitis should address local antibiotic resistance patterns. As our local data showed a less than 15% resistance of Escherichia coli to co-amoxicillin (amoxicillin + clavulanic acid), we opted for this antibiotic in 2013. Subsequently, the increasing prevalence of Pseudomonas aeruginosa challenged this choice. The aim of this study was to describe the bacteriology of peritoneal swabs from cases of complicated appendicitis in our paediatric patients, and to determine the risk of infectious complications (wound and/or intra-abdominal abscesses). We designed a retrospective cohort study including all children (
ISSN:1424-3997
1424-3997
DOI:10.4414/smw.2019.20055