Primary squamous cell carcinoma of endometrium: case report and literature review

In this paper, we report a case of primary squamous cell carcinoma of the endometrium (PSCCE) with a literature review. A 64-year-old woman, was admitted because postmenopausal bleeding. The gynecological exam found bleeding from the endocervix. The pelvic ultrasound objectified uterine regular cont...

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Bibliographic Details
Published in:The Pan African medical journal 2018, Vol.30 (8), p.8-8
Main Authors: Farhane, Fatima Zahra, Alami, Zineb, Bouhafa, Touria, Elmazghi, Abderrahmane, Hassouni, Khalid
Format: Article
Language:English
Subjects:
Cancer therapies
Carcinoma, Squamous Cell - diagnosis
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - therapy
Case Report
Case reports
Cell cycle
Disease Progression
Endometrial cancer
Endometrial Neoplasms - diagnosis
Endometrial Neoplasms - pathology
Endometrial Neoplasms - therapy
Endometrium
Female
Human papillomavirus
Humans
Hysterectomy - methods
Hysteroscopy - methods
Literature reviews
Lymphatic system
Magnetic Resonance Imaging
Medical prognosis
Middle Aged
Neoplasm Staging
Patients
postmenopausal bleeding
Prognosis
Squamous cell carcinoma
Tumors
Womens health
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Summary:In this paper, we report a case of primary squamous cell carcinoma of the endometrium (PSCCE) with a literature review. A 64-year-old woman, was admitted because postmenopausal bleeding. The gynecological exam found bleeding from the endocervix. The pelvic ultrasound objectified uterine regular contours, endometrial thickened was 10 mm, the presence of an intra cavitary lesion mesuring 56/70 mm. The diagnostic hysteroscopy revealed a whitish appearance taking all the uterine cavity making evoke a tumor of the endometrium. Pelvic MRI showed a tumor limited to the uterine corpus endometrium (invasion by more than 50% of the myometrium) without invasion of the cervix. Radical hysterectomy, bilateral salpingo-oophorectomy, and lymph nodes dissection were performed. Grossly, the endometrial carcinoma was polypoid tumor occupying the entire uterine cavity. Histologically, the diagnosis of SCC was retained. No adenocarcinoma element was recognized. Neither squamous metaplasia nor dysplasia was recognized. No ectopic cervical tissue was found. The SCC was found to invade into deeper one half of the myometrium. No tumor cells were seen in other sites including the cervix, ovaries, parametres, and lymph nodes. The patients was FIGO 2009 stage IB (pT1B, N0), and was treated with adjuvant radiation. The patient had a disease progression in the pelvis 3 months after the irradiation. We reported a case of PSCCE which can help to enrich the literature for the treatment and prognosis of this disease.
ISSN:1937-8688
1937-8688
DOI:10.11604/pamj.2018.30.8.8983