Significance of Diabetic Kidney Disease Biomarkers in Predicting Metabolic-Associated Fatty Liver Disease

Metabolic-associated fatty liver disease (MAFLD) and diabetic kidney disease (DKD) share various pathophysiological factors, and epidemiological evidence suggests that these two diseases are associated. Albuminuria and the estimated glomerular filtration rate, which are conventional biomarkers of DK...

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Bibliographic Details
Published in:Biomedicines 2023-07, Vol.11 (7), p.1928
Main Authors: Bae, Jaehyun, Lee, Byung-Wan
Format: Article
Language:English
Subjects:
Biological markers
biomarker
Biomarkers
Body fat
Diabetes
Diabetes mellitus
diabetic kidney disease
Epidemiology
Fatty acids
Fatty liver
Glomerular filtration rate
Hyperglycemia
Inflammation
Insulin resistance
Kidney diseases
Kinases
Liver diseases
Longitudinal studies
Medical research
Medicine, Experimental
metabolic-associated fatty liver disease
Metabolism
Metabolites
Obesity
Oxidative stress
Proteins
Resveratrol
Review
Risk factors
Type 2 diabetes
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Summary:Metabolic-associated fatty liver disease (MAFLD) and diabetic kidney disease (DKD) share various pathophysiological factors, and epidemiological evidence suggests that these two diseases are associated. Albuminuria and the estimated glomerular filtration rate, which are conventional biomarkers of DKD, are reportedly associated with the risk or severity of MAFLD. Recently, novel DKD biomarkers reflecting renal tubular injury have been introduced to complement conventional DKD markers. In this article, we looked at previous studies that showed an association between MAFLD and DKD, and also reviewed the significance of DKD biomarkers as predictive risk factors for MAFLD.
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines11071928