Antibody responses after COVID-19 infection in patients who are mildly symptomatic or asymptomatic in Bangladesh

•Serum IgG developed in 95% mildly symptomatic patients by day 14 and all seroconverted by day 30.•Serum IgM and IgA antibody responses were lower and less frequent than corresponding IgG responses.•Serum IgM and IgA responses peaked and declined earlier in 100% of mild symptomatic individuals.•...

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Bibliographic Details
Published in:International journal of infectious diseases 2020-12, Vol.101, p.220-225
Main Authors: Shirin, Tahmina, Bhuiyan, Taufiqur Rahman, Charles, Richelle C., Amin, Shaheena, Bhuiyan, Imran, Kawser, Zannat, Rahat, Asifuzaman, Alam, Ahmed Nawsher, Sultana, Sharmin, Aleem, Md Abdul, Khan, Manjur Hossain, Khan, Samsad Rabbani, LaRocque, Regina C., Calderwood, Stephen B., Ryan, Edward T., Slater, Damien M., Banu, Sayera, Clemens, John, Harris, Jason B., Flora, Meerjady Sabrina, Qadri, Firdausi
Format: Article
Language:English
Subjects:
Adult
Antibodies, Viral - blood
Antibodies, Viral - immunology
Antibody Formation
Asymptomatic
Bangladesh - epidemiology
Carrier State - blood
Carrier State - epidemiology
Carrier State - immunology
Carrier State - virology
COVID-19
COVID-19 - blood
COVID-19 - epidemiology
COVID-19 - immunology
COVID-19 - virology
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immune responses
Immunoglobulin G - blood
Immunoglobulin G - immunology
Immunoglobulin M - blood
Immunoglobulin M - immunology
Male
Middle Aged
Pandemics
SARS-CoV-2 - genetics
SARS-CoV-2 - immunology
Seroconversion
Symptomatic
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Description
Summary:•Serum IgG developed in 95% mildly symptomatic patients by day 14 and all seroconverted by day 30.•Serum IgM and IgA antibody responses were lower and less frequent than corresponding IgG responses.•Serum IgM and IgA responses peaked and declined earlier in 100% of mild symptomatic individuals.•
ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2020.09.1484