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The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study
The aim of this study was to verify the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on physical capacity, body composition and the value of biochemical parameters in highly-trained combat sports athletes. Forty-two males highly-trained in combat sports were subjected to 12 weeks...
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Published in: | Nutrients 2017-07, Vol.9 (7), p.753 |
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description | The aim of this study was to verify the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on physical capacity, body composition and the value of biochemical parameters in highly-trained combat sports athletes. Forty-two males highly-trained in combat sports were subjected to 12 weeks of supplementation with HMB and a placebo in a randomized, placebo controlled, double-blind crossover manner. Over the course of the experiment, aerobic and anaerobic capacity was determined, while analyses were conducted on body composition and levels of creatine kinase, lactate dehydrogenase, testosterone, cortisol and lactate. Following HMB supplementation, fat-free mass increased (
= 0.049) with a simultaneous reduction of fat mass (
= 0.016) in comparison to placebo. In turn, after HMB supplementation, the following indicators increased significantly in comparison to the placebo: the time to reach ventilatory threshold (
< 0.0001), threshold load (
= 0.017) and the threshold HR (
< 0.0001), as well as anaerobic peak power (
= 0.005), average power (
= 0.029), maximum speed (
< 0.001) and post-exercise lactate concentrations (
< 0.0001). However, when compared to the placebo, no differences were observed in blood marker levels. The results indicate that supplying HMB promotes advantageous changes in body composition and stimulates an increase in aerobic and anaerobic capacity in combat sports athletes. |
doi_str_mv | 10.3390/nu9070753 |
format | article |
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= 0.049) with a simultaneous reduction of fat mass (
= 0.016) in comparison to placebo. In turn, after HMB supplementation, the following indicators increased significantly in comparison to the placebo: the time to reach ventilatory threshold (
< 0.0001), threshold load (
= 0.017) and the threshold HR (
< 0.0001), as well as anaerobic peak power (
= 0.005), average power (
= 0.029), maximum speed (
< 0.001) and post-exercise lactate concentrations (
< 0.0001). However, when compared to the placebo, no differences were observed in blood marker levels. The results indicate that supplying HMB promotes advantageous changes in body composition and stimulates an increase in aerobic and anaerobic capacity in combat sports athletes.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu9070753</identifier><identifier>PMID: 28708126</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>adaptation ; Adult ; Aerobic capacity ; Athletes ; Biomarkers - blood ; Body composition ; Body Composition - drug effects ; Body fat ; Combat sports ; Cortisol ; Creatine ; Creatine kinase ; Creatine Kinase - blood ; Cross-Over Studies ; Crossovers ; Dietary Supplements ; Double-Blind Method ; Double-blind studies ; Fat-free body mass ; Heart Rate ; Humans ; Hydrocortisone - blood ; L-Lactate dehydrogenase ; L-Lactate Dehydrogenase - blood ; Lactate dehydrogenase ; Lactic acid ; Lactic Acid - blood ; Male ; Males ; Martial Arts ; maximal oxygen uptake ; muscle power indices ; Oxygen Consumption ; Physical Endurance - drug effects ; Physical Endurance - physiology ; Physical Exertion ; Placebos ; Poland ; Randomization ; sport ; Sports ; supplements ; Testosterone ; Testosterone - blood ; training support ; Valerates - administration & dosage ; β-hydroxy-β-methylbutyric acid</subject><ispartof>Nutrients, 2017-07, Vol.9 (7), p.753</ispartof><rights>2017. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 by the authors. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c469t-d91628502648a0f8a3096a7c4cba233324ecf77775255d0738a6d0f3fcfca5f33</citedby><cites>FETCH-LOGICAL-c469t-d91628502648a0f8a3096a7c4cba233324ecf77775255d0738a6d0f3fcfca5f33</cites><orcidid>0000-0002-5041-2981</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2108575534/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2108575534?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28708126$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Durkalec-Michalski, Krzysztof</creatorcontrib><creatorcontrib>Jeszka, Jan</creatorcontrib><creatorcontrib>Podgórski, Tomasz</creatorcontrib><title>The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>The aim of this study was to verify the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on physical capacity, body composition and the value of biochemical parameters in highly-trained combat sports athletes. Forty-two males highly-trained in combat sports were subjected to 12 weeks of supplementation with HMB and a placebo in a randomized, placebo controlled, double-blind crossover manner. Over the course of the experiment, aerobic and anaerobic capacity was determined, while analyses were conducted on body composition and levels of creatine kinase, lactate dehydrogenase, testosterone, cortisol and lactate. Following HMB supplementation, fat-free mass increased (
= 0.049) with a simultaneous reduction of fat mass (
= 0.016) in comparison to placebo. In turn, after HMB supplementation, the following indicators increased significantly in comparison to the placebo: the time to reach ventilatory threshold (
< 0.0001), threshold load (
= 0.017) and the threshold HR (
< 0.0001), as well as anaerobic peak power (
= 0.005), average power (
= 0.029), maximum speed (
< 0.001) and post-exercise lactate concentrations (
< 0.0001). However, when compared to the placebo, no differences were observed in blood marker levels. The results indicate that supplying HMB promotes advantageous changes in body composition and stimulates an increase in aerobic and anaerobic capacity in combat sports athletes.</description><subject>adaptation</subject><subject>Adult</subject><subject>Aerobic capacity</subject><subject>Athletes</subject><subject>Biomarkers - blood</subject><subject>Body composition</subject><subject>Body Composition - drug effects</subject><subject>Body fat</subject><subject>Combat sports</subject><subject>Cortisol</subject><subject>Creatine</subject><subject>Creatine kinase</subject><subject>Creatine Kinase - blood</subject><subject>Cross-Over Studies</subject><subject>Crossovers</subject><subject>Dietary Supplements</subject><subject>Double-Blind Method</subject><subject>Double-blind studies</subject><subject>Fat-free body mass</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>L-Lactate dehydrogenase</subject><subject>L-Lactate Dehydrogenase - blood</subject><subject>Lactate dehydrogenase</subject><subject>Lactic acid</subject><subject>Lactic Acid - blood</subject><subject>Male</subject><subject>Males</subject><subject>Martial Arts</subject><subject>maximal oxygen uptake</subject><subject>muscle power indices</subject><subject>Oxygen Consumption</subject><subject>Physical Endurance - drug effects</subject><subject>Physical Endurance - physiology</subject><subject>Physical Exertion</subject><subject>Placebos</subject><subject>Poland</subject><subject>Randomization</subject><subject>sport</subject><subject>Sports</subject><subject>supplements</subject><subject>Testosterone</subject><subject>Testosterone - blood</subject><subject>training support</subject><subject>Valerates - administration & dosage</subject><subject>β-hydroxy-β-methylbutyric acid</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdktGK1DAUhoso7rLuhS8gAW92wWqatEnrhTAzrs7CiuKMeBnS5GTaMW1qmi72yXw9W2cddg2B5CQfH4efE0XPE_ya0gK_aYcCc8wz-ig6JZiTmLGUPr53P4nO-36P5zVxjD6NTkjOcZ4Qdhr93laArowBFZAzSKKExN8BfqAlBBlXo_bu1xiXc9FAqEZbDmH0MgC6WH9aXqLN0HUWGmiDDLVr0bTX9a6yY7z1sm5Bo5VrShnQpnM-9GgRKgsB-rdogb7KVrum7kG_Qu_dUFqIl7Zup-qLlQpKF69cG7yzdtZ41_fuFjzahEGPz6InRtoezu_Os-jbh6vtah3ffP54vVrcxCplRYh1kTCSZ5iwNJfY5JLigkmuUlVKQiklKSjDp5WRLNOY01wyjQ01yiiZGUrPouuDVzu5F52vG-lH4WQt_j44vxPSh1pZEAUzLMeKkoTzNNOQc1qkLEmpZtIkZHa9O7i6oWxAqyk0L-0D6cOftq7Ezt2KLKM8Z3wSXNwJvPs5QB_ElJ4Ca2ULbuhFUhCcFDTLZ_Tlf-jeDb6dohIkwXnGJ2c6UZcHSs3pejDHZhIs5ukSx-ma2Bf3uz-S_2aJ_gHkvco_</recordid><startdate>20170714</startdate><enddate>20170714</enddate><creator>Durkalec-Michalski, Krzysztof</creator><creator>Jeszka, Jan</creator><creator>Podgórski, Tomasz</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-5041-2981</orcidid></search><sort><creationdate>20170714</creationdate><title>The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study</title><author>Durkalec-Michalski, Krzysztof ; Jeszka, Jan ; Podgórski, Tomasz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c469t-d91628502648a0f8a3096a7c4cba233324ecf77775255d0738a6d0f3fcfca5f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>adaptation</topic><topic>Adult</topic><topic>Aerobic capacity</topic><topic>Athletes</topic><topic>Biomarkers - blood</topic><topic>Body composition</topic><topic>Body Composition - drug effects</topic><topic>Body fat</topic><topic>Combat sports</topic><topic>Cortisol</topic><topic>Creatine</topic><topic>Creatine kinase</topic><topic>Creatine Kinase - blood</topic><topic>Cross-Over Studies</topic><topic>Crossovers</topic><topic>Dietary Supplements</topic><topic>Double-Blind Method</topic><topic>Double-blind studies</topic><topic>Fat-free body mass</topic><topic>Heart Rate</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>L-Lactate dehydrogenase</topic><topic>L-Lactate Dehydrogenase - blood</topic><topic>Lactate dehydrogenase</topic><topic>Lactic acid</topic><topic>Lactic Acid - blood</topic><topic>Male</topic><topic>Males</topic><topic>Martial Arts</topic><topic>maximal oxygen uptake</topic><topic>muscle power indices</topic><topic>Oxygen Consumption</topic><topic>Physical Endurance - drug effects</topic><topic>Physical Endurance - physiology</topic><topic>Physical Exertion</topic><topic>Placebos</topic><topic>Poland</topic><topic>Randomization</topic><topic>sport</topic><topic>Sports</topic><topic>supplements</topic><topic>Testosterone</topic><topic>Testosterone - blood</topic><topic>training support</topic><topic>Valerates - administration & dosage</topic><topic>β-hydroxy-β-methylbutyric acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Durkalec-Michalski, Krzysztof</creatorcontrib><creatorcontrib>Jeszka, Jan</creatorcontrib><creatorcontrib>Podgórski, Tomasz</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Durkalec-Michalski, Krzysztof</au><au>Jeszka, Jan</au><au>Podgórski, Tomasz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2017-07-14</date><risdate>2017</risdate><volume>9</volume><issue>7</issue><spage>753</spage><pages>753-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>The aim of this study was to verify the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on physical capacity, body composition and the value of biochemical parameters in highly-trained combat sports athletes. Forty-two males highly-trained in combat sports were subjected to 12 weeks of supplementation with HMB and a placebo in a randomized, placebo controlled, double-blind crossover manner. Over the course of the experiment, aerobic and anaerobic capacity was determined, while analyses were conducted on body composition and levels of creatine kinase, lactate dehydrogenase, testosterone, cortisol and lactate. Following HMB supplementation, fat-free mass increased (
= 0.049) with a simultaneous reduction of fat mass (
= 0.016) in comparison to placebo. In turn, after HMB supplementation, the following indicators increased significantly in comparison to the placebo: the time to reach ventilatory threshold (
< 0.0001), threshold load (
= 0.017) and the threshold HR (
< 0.0001), as well as anaerobic peak power (
= 0.005), average power (
= 0.029), maximum speed (
< 0.001) and post-exercise lactate concentrations (
< 0.0001). However, when compared to the placebo, no differences were observed in blood marker levels. The results indicate that supplying HMB promotes advantageous changes in body composition and stimulates an increase in aerobic and anaerobic capacity in combat sports athletes.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>28708126</pmid><doi>10.3390/nu9070753</doi><orcidid>https://orcid.org/0000-0002-5041-2981</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | adaptation Adult Aerobic capacity Athletes Biomarkers - blood Body composition Body Composition - drug effects Body fat Combat sports Cortisol Creatine Creatine kinase Creatine Kinase - blood Cross-Over Studies Crossovers Dietary Supplements Double-Blind Method Double-blind studies Fat-free body mass Heart Rate Humans Hydrocortisone - blood L-Lactate dehydrogenase L-Lactate Dehydrogenase - blood Lactate dehydrogenase Lactic acid Lactic Acid - blood Male Males Martial Arts maximal oxygen uptake muscle power indices Oxygen Consumption Physical Endurance - drug effects Physical Endurance - physiology Physical Exertion Placebos Poland Randomization sport Sports supplements Testosterone Testosterone - blood training support Valerates - administration & dosage β-hydroxy-β-methylbutyric acid |
title | The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study |
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