Dietary carnosic acid, selenized yeast, selenate and fish oil affected the concentration of fatty acids, tocopherols, cholesterol and aldehydes in the brains of lambs

• Published in: Archiv für Tierzucht 2016-05, Vol.59 (2), p.215-226
• Main Authors: Rozbicka-Wieczorek, Agnieszka J, Krajewska-Bienias, Katarzyna A, Czauderna, Marian
• Format: Article
• Language: English
• Subjects: Aldehydes; Animal health; Body weight; Brain; Cholesterol; Diet; Diterpenes; Experiments; Fatty acids; Fish oils; Food and nutrition; Gene expression; Health aspects; Lambs; Malondialdehyde; Metabolism; Metabolites; Organs; Oxidative stress; Peroxidation; Physiological aspects; Physiology; Polyunsaturated fatty acids; Proteins; Rapeseed; Rapeseed oil; Reproductive system; Selenium; Selenium compounds; Signal transduction; Soybeans; Tocopherols; Yeast; Yeasts; Yeasts (Fungi)
• ISSN: 2363-9822; 0003-9438; 2363-9822
• DOI: 10.5194/aab-59-215-2016

The function of the brain is to exert centralized control over the other internal organs and tissues of the body. Thus, the objective of our studies was to evaluate changes in the concentration of fatty acids (FAs), cholesterol (CHOL), cholest-4-en-3-one (CHOL-4-3), tocopherols, malondialdehyde (MDA) and fatty aldehydes in the brains of lambs fed supplemented diets. Thirty male Corriedale lambs with a body weight of 30.5 ± 2.6 kg were allotted to five groups of six lambs and housed individually. After the preliminary period, for 35 days the animals were fed a diet containing 3 % rapeseed oil (RO) (the RO diet), a diet enriched with 2 % RO and 1 % fish oil (FO) (the FO diet) or the diets with combined addition of 2 % RO, 1 % FO, 0.1 % carnosic acid (CA) (the CA diet) and 0.35 ppm Se as the selenized yeast (SeY) (the CASeY diet) or selenate (SeVI) (the CASeVI diet). The CASeVI diet most efficiently increased the accumulation of FAs (including unsaturated FAs), CHOL-4-3 and fatty aldehydes in the lamb brain. This diet most effectively decreased the concentration of CHOL and MDA in the brain. The CASeY diet showed a different impact on the level of FAs, CHOL, CHOL-4-3, tocopherols, MDA and fatty aldehydes in the brain as compared with the CASeVI diet. The CA diet reduced the concentration of CHOL-4-3, the sums of fatty aldehydes, FAs, atherogenic- and thrombogenic-saturated FAs in the brain compared with the CASeVI diet; the CA diet most effectively increased the value of polyunsaturated FA (PUFA) peroxidation index in the brain. The RO diet most efficiently increased the concentration of CHOL and values of the ratios of saturated FAs to PUFAs and long-chain n-6PUFAs to long-chain n-3PUFAs in the brain.The current studies provide new useful information for nutritionists carrying out further investigations aimed at improving farm-animal health, growth performance, reproductive system and the nutritional quality of feed for ruminants.