Costs of hospitalization in preterm infants: impact of antenatal steroid therapy

To estimate the costs of hospitalization in premature infants exposed or not to antenatal corticosteroids (ACS). Retrospective cohort analysis of premature infants with gestational age of 26–32 weeks without congenital malformations, born between January of 2006 and December of 2009 in a tertiary, p...

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Bibliographic Details
Published in:Jornal de pediatria 2016-01, Vol.92 (1), p.24-31
Main Authors: Ogata, Joice Fabiola Meneguel, Fonseca, Marcelo Cunio Machado, Miyoshi, Milton Harumi, de Almeida, Maria Fernanda Branco, Guinsburg, Ruth
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
Brazil
Costs and cost analysis
Custos e análise de custos
Female
Gestational Age
Glucocorticoides
Glucocorticoids
Hospital Costs
Hospitalization
Hospitalization - economics
Hospitalização
Hospitals, University - economics
Humans
Infant, Low Birth Weight - growth & development
Infant, Newborn
Infant, Premature - growth & development
Male
PEDIATRICS
Pregnancy
Prematuro
Preterm infant
Retrospective Studies
Tertiary Care Centers - economics
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Summary:To estimate the costs of hospitalization in premature infants exposed or not to antenatal corticosteroids (ACS). Retrospective cohort analysis of premature infants with gestational age of 26–32 weeks without congenital malformations, born between January of 2006 and December of 2009 in a tertiary, public university hospital. Maternal and neonatal demographic data, neonatal morbidities, and hospital inpatient services during the hospitalization were collected. The costs were analyzed using the microcosting technique. Of 220 patients that met the inclusion criteria, 211 (96%) charts were reviewed: 170 newborns received at least one dose of antenatal corticosteroid and 41 did not receive the antenatal medication. There was a 14–37% reduction of the different cost components in infants exposed to ACS when the entire population was analyzed, without statistical significance. Regarding premature infants who were discharged alive, there was a 24–47% reduction of the components of the hospital services costs for the ACS group, with a significant decrease in the length of stay in the neonatal intensive care unit (NICU). In very-low birth weight infants, considering only the survivors, ACS promoted a 30–50% reduction of all elements of the costs, with a 36% decrease in the total cost (p=0.008). The survivors with gestational age
ISSN:0021-7557
1678-4782
1678-4782
DOI:10.1016/j.jped.2015.03.004