Predictor parameters for poor prognosis in patients with sudden sensorineural hearing loss: fibrinogen to albumin ratio vs C-reactive protein to albumin ratio

• Published in: Brazilian journal of otorhinolaryngology 2021-07, Vol.87 (4), p.457-461
• Main Authors: Cayir, Serkan, Kayabasi, Serkan, Hizli, Omer
• Format: Article
• Language: English
• Subjects: Albumin; C-reactive protein; Fibrinogen; Original; OTORHINOLARYNGOLOGY; Sudden sensorineural hearing loss
• ISSN: 1808-8694; 1808-8686; 1808-8686
• DOI: 10.1016/j.bjorl.2020.06.010

Prognosis of sudden sensorineural hearing loss may be predicted using several parameters of laboratory blood analysis. To identify and investigate the most significant indicator parameters related to the poor prognosis of sudden sensorineural hearing loss. Eighty-eight patients were included, and three groups were constituted: non-recovery group with14 patients, recovery group with 33 patients and control group with 41 individuals. We compared fibrinogen-to-albumin ratio, C-reactive protein-to-albumin ratio, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, white blood cell and hemoglobin of the groups. Then, we investigated the most significant indicator parameters related to the poor prognosis of sudden hearing loss. The mean hemoglobin, mean platelet-lymphocyte ratio and median white blood cell values did not significantly differ among three groups (p=0.36, p=0.86 and p=0.79, respectively). A significant difference of median fibrinogen-albumin ratio, C-reactive protein-albumin ratio, neutrophil-to-lymphocyte ratio was evident among three groups (p