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Antifungal Susceptibility Testing of Fusarium: A Practical Approach
In vitro susceptibility testing of is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI)...
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Published in: | Journal of fungi (Basel) 2017-04, Vol.3 (2), p.19 |
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creator | Al-Hatmi, Abdullah M S Curfs-Breuker, Ilse de Hoog, G Sybren Meis, Jacques F Verweij, Paul E |
description | In vitro susceptibility testing of
is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility (EUCAST), but breakpoints (BPs) have not yet been established. One of the problems is that phylogenetic distances between
species are much smaller than between species of, e.g.,
. Epidemiological cutoff values (ECVs) for some
species have been determined in order to differentiate wild-type from non-wild-type isolates. In clinical routine, commercially available assays such as Etest, Sensititre or others provide essential agreement with reference methods. Our objective is to summarize antifungal susceptibility testing of
genus in the clinical laboratory: how to do it, when to do it, and how to interpret it. |
doi_str_mv | 10.3390/jof3020019 |
format | article |
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is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility (EUCAST), but breakpoints (BPs) have not yet been established. One of the problems is that phylogenetic distances between
species are much smaller than between species of, e.g.,
. Epidemiological cutoff values (ECVs) for some
species have been determined in order to differentiate wild-type from non-wild-type isolates. In clinical routine, commercially available assays such as Etest, Sensititre or others provide essential agreement with reference methods. Our objective is to summarize antifungal susceptibility testing of
genus in the clinical laboratory: how to do it, when to do it, and how to interpret it.</description><identifier>ISSN: 2309-608X</identifier><identifier>EISSN: 2309-608X</identifier><identifier>DOI: 10.3390/jof3020019</identifier><identifier>PMID: 29371537</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Breakpoints ; clinical laboratory ; CLSI ; Epidemiology ; Etest ; EUCAST ; Fungi ; Fusarium ; Hospitals ; Identification ; Infections ; Infectious diseases ; Laboratories ; Methods ; Morphology ; Peptides ; Phylogeny ; Proteins ; Review ; RNA polymerase ; Species ; Substance abuse treatment ; susceptibility test</subject><ispartof>Journal of fungi (Basel), 2017-04, Vol.3 (2), p.19</ispartof><rights>2017. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 by the authors. 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-c07716e4c96e3db941a77c9568cad488e502f7ed9b479704af470f2f7c57484b3</citedby><cites>FETCH-LOGICAL-c538t-c07716e4c96e3db941a77c9568cad488e502f7ed9b479704af470f2f7c57484b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2124671960/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2124671960?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25752,27923,27924,37011,37012,44589,53790,53792,74997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29371537$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al-Hatmi, Abdullah M S</creatorcontrib><creatorcontrib>Curfs-Breuker, Ilse</creatorcontrib><creatorcontrib>de Hoog, G Sybren</creatorcontrib><creatorcontrib>Meis, Jacques F</creatorcontrib><creatorcontrib>Verweij, Paul E</creatorcontrib><title>Antifungal Susceptibility Testing of Fusarium: A Practical Approach</title><title>Journal of fungi (Basel)</title><addtitle>J Fungi (Basel)</addtitle><description>In vitro susceptibility testing of
is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility (EUCAST), but breakpoints (BPs) have not yet been established. One of the problems is that phylogenetic distances between
species are much smaller than between species of, e.g.,
. Epidemiological cutoff values (ECVs) for some
species have been determined in order to differentiate wild-type from non-wild-type isolates. In clinical routine, commercially available assays such as Etest, Sensititre or others provide essential agreement with reference methods. Our objective is to summarize antifungal susceptibility testing of
genus in the clinical laboratory: how to do it, when to do it, and how to interpret it.</description><subject>Breakpoints</subject><subject>clinical laboratory</subject><subject>CLSI</subject><subject>Epidemiology</subject><subject>Etest</subject><subject>EUCAST</subject><subject>Fungi</subject><subject>Fusarium</subject><subject>Hospitals</subject><subject>Identification</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Laboratories</subject><subject>Methods</subject><subject>Morphology</subject><subject>Peptides</subject><subject>Phylogeny</subject><subject>Proteins</subject><subject>Review</subject><subject>RNA polymerase</subject><subject>Species</subject><subject>Substance abuse treatment</subject><subject>susceptibility test</subject><issn>2309-608X</issn><issn>2309-608X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdkV9rFDEUxYMottS--AFkwBcRVm_-TDLXB2FZbC0UFKzgW8hkMtsss5MxmRH67b11a219SnLvj8PJOYy95PBOSoT3u9RLEAAcn7BjIQFXGpofTx_cj9hpKTsgpG40onzOjgRKw2tpjtlmPc6xX8atG6pvS_FhmmMbhzjfVFehzHHcVqmvzpbiclz2H6p19TU7P0dP_HqacnL--gV71ruhhNO784R9P_t0tfm8uvxyfrFZX658LZt55cEYroPyqIPsWlTcGeOx1o13nWqaUIPoTeiwVQYNKNcrAz2NfG1Uo1p5wi4Oul1yOzvluHf5xiYX7Z9BylvrMlkbgkXjpQDULWiv6OetaYwKnacHqfKOtD4etKal3dMijHN2wyPRx5sxXttt-mVrCg6FIIE3dwI5_VwoKruPFN8wuDGkpViOSK1gDZLQ1_-hu7TkkaKyggulDUcNRL09UD6nUnLo781wsLdV239VE_zqof179G-x8jfq7KK8</recordid><startdate>20170426</startdate><enddate>20170426</enddate><creator>Al-Hatmi, Abdullah M S</creator><creator>Curfs-Breuker, Ilse</creator><creator>de Hoog, G Sybren</creator><creator>Meis, Jacques F</creator><creator>Verweij, Paul E</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20170426</creationdate><title>Antifungal Susceptibility Testing of Fusarium: A Practical Approach</title><author>Al-Hatmi, Abdullah M S ; 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is becoming increasingly important because of frequency and diversity of infections and because resistance profiles are species-specific. Reference methods for antifungal susceptibility testing (AFST) are those of Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility (EUCAST), but breakpoints (BPs) have not yet been established. One of the problems is that phylogenetic distances between
species are much smaller than between species of, e.g.,
. Epidemiological cutoff values (ECVs) for some
species have been determined in order to differentiate wild-type from non-wild-type isolates. In clinical routine, commercially available assays such as Etest, Sensititre or others provide essential agreement with reference methods. Our objective is to summarize antifungal susceptibility testing of
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subjects | Breakpoints clinical laboratory CLSI Epidemiology Etest EUCAST Fungi Fusarium Hospitals Identification Infections Infectious diseases Laboratories Methods Morphology Peptides Phylogeny Proteins Review RNA polymerase Species Substance abuse treatment susceptibility test |
title | Antifungal Susceptibility Testing of Fusarium: A Practical Approach |
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