Radiomics nomogram based on dual-energy spectral CT imaging to diagnose low bone mineral density

Osteoporosis is associated with a decrease of bone mineralized component as well as a increase of bone marrow fat. At present, there are few studies using radiomics nomogram based fat-water material decomposition (MD) images of dual-energy spectral CT as an evaluation method of abnormally low Bone M...

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Bibliographic Details
Published in:BMC musculoskeletal disorders 2022-05, Vol.23 (1), p.424-424, Article 424
Main Authors: Yao, Qianqian, Liu, Mengke, Yuan, Kemei, Xin, Yue, Qiu, Xiaoqian, Zheng, Xiuzhu, Li, Changqin, Duan, Shaofeng, Qin, Jian
Format: Article
Language:English
Subjects:
Absorptiometry
Body mass index
Bone density
Bone imaging
Bone marrow
Bone mineral density
Bones
Computed tomography
CT imaging
Density
Dual energy X-ray absorptiometry
Dual-energy spectral CT
Energy
Fractures
Gender
Medical records
Methods
Musculoskeletal diseases
Nomograms
Nomography (Mathematics)
Osteoporosis
Patients
Performance evaluation
Radiomics
Risk factors
Software
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Summary:Osteoporosis is associated with a decrease of bone mineralized component as well as a increase of bone marrow fat. At present, there are few studies using radiomics nomogram based fat-water material decomposition (MD) images of dual-energy spectral CT as an evaluation method of abnormally low Bone Mineral Density (BMD). This study aims to establish and validate a radiomics nomogram based the fat-water imaging of dual-energy spectral CT in diagnosing low BMD. Ninety-five patients who underwent dual-energy spectral CT included T11-L2 and dual x-ray absorptiometry (DXA) were collected. The patients were divided into two groups according to T-score, normal BMD(T ≥ -1) and abnormally low BMD (T 
ISSN:1471-2474
1471-2474
DOI:10.1186/s12891-022-05389-4