Procalcitonin as an early marker in the detection of anastomotic intestinal leak in a Universitary Hospital of Bogotá

• Published in: Journal of Coloproctology 2020-12, Vol.40 (4), p.376-385
• Main Authors: Navarrete, Elkin Eduardo Benítez, Beltrán-García, Tatiana Carolina, Mosquera, María Fernanda, Rojas, Valeria Martinez, Medina, Daniel Alejandro Buitrago, Avendaño, Carlos Edgar Figueroa
• Format: Article
• Language: English
• Subjects: Anastomotic fistula; Cirurgia colorretal; Colorectal surgery; Detecção precoce; Early detection; Fístula anastomótica; GASTROENTEROLOGY & HEPATOLOGY; Original Article; Procalcitonin; Procalcitonina; SURGERY
• ISSN: 2237-9363; 2317-6423; 2317-6423
• DOI: 10.1016/j.jcol.2020.07.005

Anastomotic leakage is a complication of intestinal anastomosis, with an incidence of 2%–7% in centers of experience. To be able to achieve an early detection, serological markers such as Procalcitonin were included. Descriptive retrospective cohort study of patients taken to colorectal surgery with intestinal anastomosis, the objective is to estimate association between procalcitonin (≥2 ng/dl) as an early inflammatory marker and anastomotic leakage in a Coloproctological Service of a highest level of health care hospital, between September 2017 and January 2019. Cohort of 237 patients, 51% women (18–89 years), with multiple comorbidities in 81% of patients, colon cancer was the most operated pathology (53.1%). Laparoscopic approach was the most applied 60.34%, colorectal anastomosis was the most frequently performed (47.26%). Ileocolic anastomosis presented a higher frequency (43.75%-n:7) of dehiscence. Anastomotic leakage was associated with a serum procalcitonin positive 3 days postoperatively (p-value