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Particular matter influences the incidence of acute otitis media in children
Particulate matter (PM) is the main component of air pollution. Children are vulnerable to PM and acute otitis media (AOM), which is one of the most common diseases in children. However, studies on the relationship between AOM in children and PM are rare and their results are inconsistent. The aim o...
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| Published in: | Scientific reports 2021-10, Vol.11 (1), p.19730-19730, Article 19730 |
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| creator | Park, Mina Han, Jiyeon Park, Jiwon Jang, Myoung-jin Park, Moo Kyun |
| description | Particulate matter (PM) is the main component of air pollution. Children are vulnerable to PM and acute otitis media (AOM), which is one of the most common diseases in children. However, studies on the relationship between AOM in children and PM are rare and their results are inconsistent. The aim of this study is to investigate the effect of PM on AOM in children on the basis of the Korea National Health Insurance service (NHIS) claims data. NHIS claim data from 2008 to 2015 was used to identify outpatient visits, antibiotic use to treat AOM, and demographic data. This data was combined with the data on PM
2.5
(≤ 2.5 μm) and PM
10
(≤ 10 μm according to its aerodynamic diameter) level extracted from air pollution data from Korean National Institute of Environmental Research for 16 administrative regions. The children with AOM were divided into three age groups ( |
| doi_str_mv | 10.1038/s41598-021-99247-3 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_980e3853dd3d4b2a93ab5adfa9c5f82b</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_980e3853dd3d4b2a93ab5adfa9c5f82b</doaj_id><sourcerecordid>2579629928</sourcerecordid><originalsourceid>FETCH-LOGICAL-c540t-e67a58c2249a7575e57a84dd08fd44faffb01d39f1abe6115ab9d1eda269c0a63</originalsourceid><addsrcrecordid>eNp9kU1v1DAQhiMEolXpH-CAInHhEvBnYl-QUAW00kpwgLM1sce7XmXjYjtI_fe4m7a0HPDFHs8zr2f8Ns1rSt5TwtWHLKjUqiOMdlozMXT8WXPKiJAd44w9f3Q-ac5z3pO6JNOC6pfNCRc9pUzQ02bzHVIJdpkgtQcoBVMbZj8tOFvMbdlhDW1wt2EbfQt2KfVQQgm5PaALUPOt3YXJJZxfNS88TBnP7_az5ueXzz8uLrvNt69XF582nZWClA77AaSyjAkNgxwkygGUcI4o74Tw4P1IqOPaUxixNiph1I6iA9ZrS6DnZ83Vqusi7M11CgdINyZCMMeLmLbmONWERiuCXEnuHHdiZKA5jBKcB22lV2ysWh9XretlrANZnEuC6Yno08wcdmYbfxslNOsHWQXe3Qmk-GvBXMwhZIvTBDPGJRsmB92z6pGq6Nt_0H1c0ly_6kgxMnCiK8VWyqaYc0L_0Awl5tZ7s3pvqvfm6L3htejN4zEeSu6drgBfgVxT8xbT37f_I_sHJsG68A</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2579207309</pqid></control><display><type>article</type><title>Particular matter influences the incidence of acute otitis media in children</title><source>Open Access: PubMed Central</source><source>Full-Text Journals in Chemistry (Open access)</source><source>Publicly Available Content (ProQuest)</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Park, Mina ; Han, Jiyeon ; Park, Jiwon ; Jang, Myoung-jin ; Park, Moo Kyun</creator><creatorcontrib>Park, Mina ; Han, Jiyeon ; Park, Jiwon ; Jang, Myoung-jin ; Park, Moo Kyun</creatorcontrib><description>Particulate matter (PM) is the main component of air pollution. Children are vulnerable to PM and acute otitis media (AOM), which is one of the most common diseases in children. However, studies on the relationship between AOM in children and PM are rare and their results are inconsistent. The aim of this study is to investigate the effect of PM on AOM in children on the basis of the Korea National Health Insurance service (NHIS) claims data. NHIS claim data from 2008 to 2015 was used to identify outpatient visits, antibiotic use to treat AOM, and demographic data. This data was combined with the data on PM
2.5
(≤ 2.5 μm) and PM
10
(≤ 10 μm according to its aerodynamic diameter) level extracted from air pollution data from Korean National Institute of Environmental Research for 16 administrative regions. The children with AOM were divided into three age groups (< 2, 2–4, 5–10 years). Generalized linear Poisson regression model was used to estimate the association between AOM and PM using daily counts of AOM and daily mean PM concentrations. It was adjusted to temperature, wind, humidity, season, year, age, and region. With an increase in PM
2.5
of 10 μg/m
3
, the relative risk of OM increased by 4.5% in children under 2 years of age. The effect of PM
2.5
was strongest influence on the day of exposure. The exposure to PM
10
was related to the incidence of AOM on the day of exposure and the following seven days in all three age groups. The PM concentrations did not strongly affect either AOM duration or the use of antibiotics to cure AOM. The RR in the each lag day after exposure to PM
10
was diverse according to the age groups. Regardless of PM size and children’s age, the PM levels are positively related to the incidence of AOM. Both PM
2.5
and PM
10
have the most adverse effects on children under 2 years of age and on the day of exposure.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-021-99247-3</identifier><identifier>PMID: 34611241</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/308 ; 692/499 ; 692/699 ; 704/172 ; 704/844 ; Acute Disease ; Age Factors ; Age groups ; Air Pollutants ; Air Pollution ; Antibiotics ; Child ; Child, Preschool ; Children ; Disease Susceptibility ; Ear diseases ; Environmental Exposure ; Environmental research ; Exposure ; Female ; Humanities and Social Sciences ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; multidisciplinary ; Otitis media ; Otitis Media - epidemiology ; Otitis Media - etiology ; Particle Size ; Particulate matter ; Particulate Matter - adverse effects ; Public Health Surveillance ; Republic of Korea - epidemiology ; Risk Factors ; Science ; Science (multidisciplinary) ; Seasons</subject><ispartof>Scientific reports, 2021-10, Vol.11 (1), p.19730-19730, Article 19730</ispartof><rights>The Author(s) 2021</rights><rights>2021. The Author(s).</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-e67a58c2249a7575e57a84dd08fd44faffb01d39f1abe6115ab9d1eda269c0a63</citedby><cites>FETCH-LOGICAL-c540t-e67a58c2249a7575e57a84dd08fd44faffb01d39f1abe6115ab9d1eda269c0a63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2579207309/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2579207309?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,74998</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34611241$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, Mina</creatorcontrib><creatorcontrib>Han, Jiyeon</creatorcontrib><creatorcontrib>Park, Jiwon</creatorcontrib><creatorcontrib>Jang, Myoung-jin</creatorcontrib><creatorcontrib>Park, Moo Kyun</creatorcontrib><title>Particular matter influences the incidence of acute otitis media in children</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Particulate matter (PM) is the main component of air pollution. Children are vulnerable to PM and acute otitis media (AOM), which is one of the most common diseases in children. However, studies on the relationship between AOM in children and PM are rare and their results are inconsistent. The aim of this study is to investigate the effect of PM on AOM in children on the basis of the Korea National Health Insurance service (NHIS) claims data. NHIS claim data from 2008 to 2015 was used to identify outpatient visits, antibiotic use to treat AOM, and demographic data. This data was combined with the data on PM
2.5
(≤ 2.5 μm) and PM
10
(≤ 10 μm according to its aerodynamic diameter) level extracted from air pollution data from Korean National Institute of Environmental Research for 16 administrative regions. The children with AOM were divided into three age groups (< 2, 2–4, 5–10 years). Generalized linear Poisson regression model was used to estimate the association between AOM and PM using daily counts of AOM and daily mean PM concentrations. It was adjusted to temperature, wind, humidity, season, year, age, and region. With an increase in PM
2.5
of 10 μg/m
3
, the relative risk of OM increased by 4.5% in children under 2 years of age. The effect of PM
2.5
was strongest influence on the day of exposure. The exposure to PM
10
was related to the incidence of AOM on the day of exposure and the following seven days in all three age groups. The PM concentrations did not strongly affect either AOM duration or the use of antibiotics to cure AOM. The RR in the each lag day after exposure to PM
10
was diverse according to the age groups. Regardless of PM size and children’s age, the PM levels are positively related to the incidence of AOM. Both PM
2.5
and PM
10
have the most adverse effects on children under 2 years of age and on the day of exposure.</description><subject>692/308</subject><subject>692/499</subject><subject>692/699</subject><subject>704/172</subject><subject>704/844</subject><subject>Acute Disease</subject><subject>Age Factors</subject><subject>Age groups</subject><subject>Air Pollutants</subject><subject>Air Pollution</subject><subject>Antibiotics</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Disease Susceptibility</subject><subject>Ear diseases</subject><subject>Environmental Exposure</subject><subject>Environmental research</subject><subject>Exposure</subject><subject>Female</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>multidisciplinary</subject><subject>Otitis media</subject><subject>Otitis Media - epidemiology</subject><subject>Otitis Media - etiology</subject><subject>Particle Size</subject><subject>Particulate matter</subject><subject>Particulate Matter - adverse effects</subject><subject>Public Health Surveillance</subject><subject>Republic of Korea - epidemiology</subject><subject>Risk Factors</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Seasons</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9kU1v1DAQhiMEolXpH-CAInHhEvBnYl-QUAW00kpwgLM1sce7XmXjYjtI_fe4m7a0HPDFHs8zr2f8Ns1rSt5TwtWHLKjUqiOMdlozMXT8WXPKiJAd44w9f3Q-ac5z3pO6JNOC6pfNCRc9pUzQ02bzHVIJdpkgtQcoBVMbZj8tOFvMbdlhDW1wt2EbfQt2KfVQQgm5PaALUPOt3YXJJZxfNS88TBnP7_az5ueXzz8uLrvNt69XF582nZWClA77AaSyjAkNgxwkygGUcI4o74Tw4P1IqOPaUxixNiph1I6iA9ZrS6DnZ83Vqusi7M11CgdINyZCMMeLmLbmONWERiuCXEnuHHdiZKA5jBKcB22lV2ysWh9XretlrANZnEuC6Yno08wcdmYbfxslNOsHWQXe3Qmk-GvBXMwhZIvTBDPGJRsmB92z6pGq6Nt_0H1c0ly_6kgxMnCiK8VWyqaYc0L_0Awl5tZ7s3pvqvfm6L3htejN4zEeSu6drgBfgVxT8xbT37f_I_sHJsG68A</recordid><startdate>20211005</startdate><enddate>20211005</enddate><creator>Park, Mina</creator><creator>Han, Jiyeon</creator><creator>Park, Jiwon</creator><creator>Jang, Myoung-jin</creator><creator>Park, Moo Kyun</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><general>Nature Portfolio</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20211005</creationdate><title>Particular matter influences the incidence of acute otitis media in children</title><author>Park, Mina ; Han, Jiyeon ; Park, Jiwon ; Jang, Myoung-jin ; Park, Moo Kyun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-e67a58c2249a7575e57a84dd08fd44faffb01d39f1abe6115ab9d1eda269c0a63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>692/308</topic><topic>692/499</topic><topic>692/699</topic><topic>704/172</topic><topic>704/844</topic><topic>Acute Disease</topic><topic>Age Factors</topic><topic>Age groups</topic><topic>Air Pollutants</topic><topic>Air Pollution</topic><topic>Antibiotics</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Disease Susceptibility</topic><topic>Ear diseases</topic><topic>Environmental Exposure</topic><topic>Environmental research</topic><topic>Exposure</topic><topic>Female</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>multidisciplinary</topic><topic>Otitis media</topic><topic>Otitis Media - epidemiology</topic><topic>Otitis Media - etiology</topic><topic>Particle Size</topic><topic>Particulate matter</topic><topic>Particulate Matter - adverse effects</topic><topic>Public Health Surveillance</topic><topic>Republic of Korea - epidemiology</topic><topic>Risk Factors</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Seasons</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Mina</creatorcontrib><creatorcontrib>Han, Jiyeon</creatorcontrib><creatorcontrib>Park, Jiwon</creatorcontrib><creatorcontrib>Jang, Myoung-jin</creatorcontrib><creatorcontrib>Park, Moo Kyun</creatorcontrib><collection>SpringerOpen</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Mina</au><au>Han, Jiyeon</au><au>Park, Jiwon</au><au>Jang, Myoung-jin</au><au>Park, Moo Kyun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Particular matter influences the incidence of acute otitis media in children</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2021-10-05</date><risdate>2021</risdate><volume>11</volume><issue>1</issue><spage>19730</spage><epage>19730</epage><pages>19730-19730</pages><artnum>19730</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Particulate matter (PM) is the main component of air pollution. Children are vulnerable to PM and acute otitis media (AOM), which is one of the most common diseases in children. However, studies on the relationship between AOM in children and PM are rare and their results are inconsistent. The aim of this study is to investigate the effect of PM on AOM in children on the basis of the Korea National Health Insurance service (NHIS) claims data. NHIS claim data from 2008 to 2015 was used to identify outpatient visits, antibiotic use to treat AOM, and demographic data. This data was combined with the data on PM
2.5
(≤ 2.5 μm) and PM
10
(≤ 10 μm according to its aerodynamic diameter) level extracted from air pollution data from Korean National Institute of Environmental Research for 16 administrative regions. The children with AOM were divided into three age groups (< 2, 2–4, 5–10 years). Generalized linear Poisson regression model was used to estimate the association between AOM and PM using daily counts of AOM and daily mean PM concentrations. It was adjusted to temperature, wind, humidity, season, year, age, and region. With an increase in PM
2.5
of 10 μg/m
3
, the relative risk of OM increased by 4.5% in children under 2 years of age. The effect of PM
2.5
was strongest influence on the day of exposure. The exposure to PM
10
was related to the incidence of AOM on the day of exposure and the following seven days in all three age groups. The PM concentrations did not strongly affect either AOM duration or the use of antibiotics to cure AOM. The RR in the each lag day after exposure to PM
10
was diverse according to the age groups. Regardless of PM size and children’s age, the PM levels are positively related to the incidence of AOM. Both PM
2.5
and PM
10
have the most adverse effects on children under 2 years of age and on the day of exposure.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>34611241</pmid><doi>10.1038/s41598-021-99247-3</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Scientific reports, 2021-10, Vol.11 (1), p.19730-19730, Article 19730 |
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| source | Open Access: PubMed Central; Full-Text Journals in Chemistry (Open access); Publicly Available Content (ProQuest); Springer Nature - nature.com Journals - Fully Open Access |
| subjects | 692/308 692/499 692/699 704/172 704/844 Acute Disease Age Factors Age groups Air Pollutants Air Pollution Antibiotics Child Child, Preschool Children Disease Susceptibility Ear diseases Environmental Exposure Environmental research Exposure Female Humanities and Social Sciences Humans Incidence Infant Infant, Newborn Male multidisciplinary Otitis media Otitis Media - epidemiology Otitis Media - etiology Particle Size Particulate matter Particulate Matter - adverse effects Public Health Surveillance Republic of Korea - epidemiology Risk Factors Science Science (multidisciplinary) Seasons |
| title | Particular matter influences the incidence of acute otitis media in children |
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