Risk factors for Trypanosoma cruzi infection among blood donors in central Brazil

Characteristics and possible risk factors associated with Trypanosoma cruzi infection among blood donors were assessed within a routine screening programme in blood banks in an endemic area of Chagas disease. 6,172 voluntary blood donors were interviewed and tested for anti-T. cruzi antibodies by Ha...

Full description

Saved in:
Bibliographic Details
Published in:Memórias do Instituto Oswaldo Cruz 1992-09, Vol.87 (3), p.339-343
Main Authors: Martelli, C M, Andrade, A L, Silva, S A, Zicker, F
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Animals
Antibodies, Protozoan - blood
Blood Donors
Brazil - epidemiology
Chagas Disease - epidemiology
Chagas Disease - prevention & control
Educational Status
Female
Humans
Income
Male
Mass Screening
Middle Aged
Odds Ratio
PARASITOLOGY
Prevalence
Risk Factors
TROPICAL MEDICINE
Trypanosoma cruzi
Trypanosoma cruzi - immunology
Trypanosoma cruzi infection
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Characteristics and possible risk factors associated with Trypanosoma cruzi infection among blood donors were assessed within a routine screening programme in blood banks in an endemic area of Chagas disease. 6,172 voluntary blood donors were interviewed and tested for anti-T. cruzi antibodies by Haemagglutination and Complement Fixation tests in six blood banks in Goiânia-Central Brazil from October 1988 to April 1989. An overall prevalence of 2.3% for T. cruzi infection was obtained, being 3.3% for first-time blood donors and 1.9% for regular ones (p < 0.01). Considering this seropositivity among regular blood donors, selection of candidates relying only on the history of previous donation was found to be inadequate. The risk of infection increased inversely with the degrees of education and monthly income. There was a 9.2 risk of infection (95% CI 3.8-22.6) for those who had lived more than 21 years in an endemic area compared to subjects who had never lived in rural settings, after multivariate analysis. These informations may help to review the criteria of selection of donors in order to improve quality of blood products in endemic areas.
ISSN:0074-0276
1678-8060
0074-0276
1678-8060
DOI:10.1590/S0074-02761992000300002