C-reactive protein for late-onset sepsis diagnosis in very low birth weight infants

Late-onset sepsis in very low birth weight (VLBW) infants is a diagnostic challenge. We aimed to evaluate the diagnostic utility of the C-Reactive protein (CRP) and the complete blood count (CBC) for late-onset sepsis in VLBW infants. In a 5-year retrospective cohort of 416 VLBW infants born at less...

Full description

Saved in:
Bibliographic Details
Published in:BMC pediatrics 2018-01, Vol.18 (1), p.16-16, Article 16
Main Authors: Beltempo, Marc, Viel-Thériault, Isabelle, Thibeault, Roseline, Julien, Anne-Sophie, Piedboeuf, Bruno
Format: Article
Language:English
Subjects:
Blood cell count
C-reactive protein
Diagnosis
Health aspects
Infants
Late-onset sepsis
Neonatology
Sepsis
Very low birth weight
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Late-onset sepsis in very low birth weight (VLBW) infants is a diagnostic challenge. We aimed to evaluate the diagnostic utility of the C-Reactive protein (CRP) and the complete blood count (CBC) for late-onset sepsis in VLBW infants. In a 5-year retrospective cohort of 416 VLBW infants born at less than 1500 g, there were 590 separate late-onset sepsis evaluations. CRP and CBC were drawn at time of initial blood culture (T0), at 16-24 h (T24) and 40-48 h (T48) after. The positive cut-off values for abnormal values were the following: CRP ≥10 mg/L and CBC with at least one anomaly, including white blood cell count  0.10, or platelet count
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-018-1002-5