Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs

To evaluate the therapeutic effects of atelocollagen absorbable punctal plugs. Seventy-four eyes in 37 patients with dry eye disease (DED) underwent punctal plug occlusion using atelocollagen plugs and were followed up for 24 weeks. Subjective symptoms were evaluated using the ocular surface disease...

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Published in:Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2012-01, Vol.6 (default), p.133-138
Main Authors: Hirai, Kaori, Takano, Yoji, Uchio, Eiichi, Kadonosono, Kazuaki
Format: Article
Language:English
Subjects:
absorbable punctual plug
atelocollagen
Care and treatment
Collagen
Dosage and administration
Drug therapy
dry eye
Dry eye syndromes
Health aspects
Ophthalmology
Short Report
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Takano, Yoji
Uchio, Eiichi
Kadonosono, Kazuaki
description To evaluate the therapeutic effects of atelocollagen absorbable punctal plugs. Seventy-four eyes in 37 patients with dry eye disease (DED) underwent punctal plug occlusion using atelocollagen plugs and were followed up for 24 weeks. Subjective symptoms were evaluated using the ocular surface disease index (OSDI) questionnaire. Ocular surface disease parameters, including the Schirmer test, phenol red thread test, tear break-up time (TBUT), and fluorescein and Rose Bengal staining, were recorded before and 1, 4, 8, 16, and 24 weeks after treatment. In comparison with the pretreatment data, the subjective symptoms and ocular surface disease parameters showed significant improvement after atelocollagen punctal occlusion. The average time of relapse was 17.4 ± 5.1 weeks. No severe complications occurred, and none of the plugs had to be removed because of local discomfort or epiphora. Atelocollagen absorbable punctal plugs effectively improved ocular surface disorders in DED. These plugs are a safe and effective alternative in the treatment of DED.
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1177-5483
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subjects absorbable punctual plug
atelocollagen
Care and treatment
Collagen
Dosage and administration
Drug therapy
dry eye
Dry eye syndromes
Health aspects
Ophthalmology
Short Report
title Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs
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