Coordination of tissue cell polarity by auxin transport and signaling

Plants coordinate the polarity of hundreds of cells during vein formation, but how they do so is unclear. The prevailing hypothesis proposes that GNOM, a regulator of membrane trafficking, positions PIN-FORMED auxin transporters to the correct side of the plasma membrane; the resulting cell-to-cell,...

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Bibliographic Details
Published in:eLife 2019-12, Vol.8
Main Authors: Verna, Carla, Ravichandran, Sree Janani, Sawchuk, Megan G, Linh, Nguyen Manh, Scarpella, Enrico
Format: Article
Language:English
Subjects:
Arabidopsis
Arabidopsis - physiology
Arabidopsis Proteins - metabolism
Arabidopsis thaliana
auxin signaling
auxin transport
Cell membranes
Cell Polarity
Cells (Biology)
Defects
Developmental Biology
Genetic research
Guanine Nucleotide Exchange Factors - metabolism
Hormones
Hypotheses
Indoleacetic Acids - metabolism
leaf development
Leaves
Localization
Membrane trafficking
Microscopy
Pattern formation
Pharmaceutical industry
Plant Biology
Plant Cells - physiology
Plant Growth Regulators - metabolism
Plant Vascular Bundle - cytology
Plant Vascular Bundle - growth & development
Plants (Organisms)
Polarity
Proteins
Scientists
Signal Transduction
tissue cell polarity
vein patterning
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Summary:Plants coordinate the polarity of hundreds of cells during vein formation, but how they do so is unclear. The prevailing hypothesis proposes that GNOM, a regulator of membrane trafficking, positions PIN-FORMED auxin transporters to the correct side of the plasma membrane; the resulting cell-to-cell, polar transport of auxin would coordinate tissue cell polarity and induce vein formation. Contrary to predictions of the hypothesis, we find that vein formation occurs in the absence of PIN-FORMED or any other intercellular auxin-transporter; that the residual auxin-transport-independent vein-patterning activity relies on auxin signaling; and that a -dependent signal acts upstream of both auxin transport and signaling to coordinate tissue cell polarity and induce vein formation. Our results reveal synergism between auxin transport and signaling, and their unsuspected control by in the coordination of tissue cell polarity during vein patterning, one of the most informative expressions of tissue cell polarization in plants.
ISSN:2050-084X
2050-084X
DOI:10.7554/elife.51061