Influence of sex and disease etiology on the development of papilledema and optic nerve sheath extension in the setting of intracranial pressure elevation in children

Dilatation of the optic nerve sheath diameter and swelling of the optic disc are known phenomena associated with intracranial pressure elevation. Do sex and disease etiology have an impact on the development of optic disc elevation and optic nerve sheath extension in children in the setting of ICP e...

Full description

Saved in:
Bibliographic Details
Published in:Brain & spine 2024-01, Vol.4, p.102729-102729, Article 102729
Main Authors: Kerscher, Susanne Regina, Tellermann, Jonas, Zipfel, Julian, Bevot, Andrea, Haas-Lude, Karin, Schuhmann, Martin Ulrich
Format: Article
Language:English
Subjects:
Etiology-specificity
Fundoscopy
ICP
ONSD
Optic nerve sheath diameter
Sex-specificity
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Dilatation of the optic nerve sheath diameter and swelling of the optic disc are known phenomena associated with intracranial pressure elevation. Do sex and disease etiology have an impact on the development of optic disc elevation and optic nerve sheath extension in children in the setting of ICP elevation? Fundoscopic papilledema and point-of-care-ultrasound techniques-optic nerve sheath diameter (US-ONSD) and optic disc elevation (US-ODE) - were compared in this regard. 72 children were included in this prospective study; 50 with proven pathology (e.g. pseudotumor cerebri, tumor), 22 with pathology excluded. Bilateral US-ONSD and US-ODE were quantified by US using a 12-MHz-linear-array-transducer. This was compared with fundoscopic optic disc findings and in 28 patients with invasive ICP values, stratified for sex and etiology. In patients with proven disease, significant more girls (69%) had fundoscopic papilledema compared with boys (37%, p 
ISSN:2772-5294
2772-5294
DOI:10.1016/j.bas.2023.102729