Antithrombotic Treatment After Surgical and Transcatheter Heart Valve Repair and Replacement

New antithrombotic drugs have been developed, new valve types have been designed and minimally invasive transcatheter techniques have emerged, making the choice of antithrombotic therapy after surgical or transcatheter heart valve repair and replacement increasingly complex. Moreover, due to a lack...

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Bibliographic Details
Published in:Frontiers in cardiovascular medicine 2021-08, Vol.8, p.702780-702780
Main Authors: Verstraete, Andreas, Herregods, Marie Christine, Verbrugghe, Peter, Lamberigts, Marie, Vanassche, Thomas, Meyns, Bart, Oosterlinck, Wouter, Rega, Filip, Adriaenssens, Tom, Van Hoof, Lucas, Keuleers, Siegmund, Vandenbriele, Christophe, Sinnaeve, Peter, Janssens, Stefan, Dubois, Christophe, Meuris, Bart, Verhamme, Peter
Format: Article
Language:English
Subjects:
anTithrombotic treatment
Cardiovascular Medicine
surgical valve repair
surgical valve replacement
transcatheter valve repair
transcatheter valve replacement
valve intervention
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Summary:New antithrombotic drugs have been developed, new valve types have been designed and minimally invasive transcatheter techniques have emerged, making the choice of antithrombotic therapy after surgical or transcatheter heart valve repair and replacement increasingly complex. Moreover, due to a lack of large randomized controlled trials many recommendations for antithrombotic therapy are based on expert opinion, reflected by divergent recommendations in current guidelines. Therefore, decision-making in clinical practice regarding antithrombotic therapy for prosthetic heart valves is difficult, potentially resulting in sub-optimal patient treatment. This article compares the 2017 ESC/EACTS and 2020 ACC/AHA guidelines on the management of valvular heart disease and summarizes the available evidence. Finally, we established a convenient consensus on antithrombotic therapy after valve interventions based on over 800 annual cases of surgical and transcatheter heart valve repair and replacement and a multidisciplinary team discussion between the department of cardiovascular diseases and cardiac surgery of the University Hospitals Leuven, Belgium.
ISSN:2297-055X
2297-055X
DOI:10.3389/fcvm.2021.702780