Dietary lysozyme and avilamycin modulate gut health, immunity, and growth rate in broilers

• Published in: BMC veterinary research 2024-01, Vol.20 (1), p.28-28, Article 28
• Main Authors: Abdel-Latif, Mervat A, El-Hamid, Hatem S Abd, Emam, Mohamed, Noreldin, Ahmed E, Helmy, Yosra A, El-Far, Ali H, Elbestawy, Ahmed R
• Format: Article
• Language: English
• Subjects: Animal Feed - analysis; Animals; Antibiotics; Antigens; Avian flu; Avilamycin; Body Weight; Body weight gain; Broilers; Broilers (Poultry); Chickens; Cytokines; Diet; Diet - veterinary; Dietary Supplements; Digestive system; Feed additives; Feeds; Gastrointestinal tract; Gene expression; Glutathione peroxidase; Gut health; Health aspects; Hemagglutination inhibition; Immune response; Immunity; Immunity (Disease); Influenza A Virus, H5N1 Subtype; Interleukin 10; Interleukin 18; Interleukin 2; Intestine; Juveniles; Kinases; Lysozyme; Microbiomes; Microbiota (Symbiotic organisms); Muramidase; Oligosaccharides; Poultry; Proteins; Vaccination; Vaccines; γ-Interferon
• ISSN: 1746-6148; 1746-6148
• DOI: 10.1186/s12917-023-03871-2

Attempts to use dietary lysozyme (LYZ) as an alternative to antibiotics in broilers have been successful, but further research is needed for effective use. Here, we compared the differences between LYZ and avilamycin (AVI) feed additives for growth performance, gut health and immunity of broilers. One-day old, one hundred and twenty broiler chicks (Ross 308) were randomly allocated into three groups consisting forty birds in each group. Standard diet without supplementation was applied as the control group (I), while the chicks of the other groups were supplemented with 100 mg of AVI per kg diet (AVI, group II), and 90 mg LYZ per kg diet (LYZ, group III) for five consecutive weeks. Body weight, feed conversion ratio, body weight gain, and European production efficiency factor were markedly (p