Hypotensive Anesthesia Combined with Tranexamic Acid Reduces Perioperative Blood Loss in Simultaneous Bilateral Total Hip Arthroplasty: A Retrospective Cohort Study

Objective To assess the efficacy and safety of hypotensive anesthesia (HA) combined with tranexamic acid (TXA) for reducing perioperative blood loss in simultaneous bilateral total hip arthroplasty (SBTHA). Methods In this retrospective cohort study, a total of 183 eligible patients (15 females and...

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Bibliographic Details
Published in:Orthopaedic surgery 2022-03, Vol.14 (3), p.555-565
Main Authors: Zhang, Qing‐Yi, Huang, Kai, Yin, Shi‐Jiu, Wang, Mi‐Ye, Liao, Ren, Xie, Hui‐Qi, Yang, Jing, Zeng, Yi
Format: Article
Language:English
Subjects:
Anemia
Antifibrinolytic agents
Binding sites
blood loss
Blood pressure
Blood transfusions
Clinical
Cohort analysis
Embolisms
General anesthesia
Hemoglobin
Hospitals
hypotensive anesthesia
Joint replacement surgery
Joint surgery
Medical records
Pain
Patients
simultaneous bilateral total hip arthroplasty
tranexamic acid
transfusion
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Summary:Objective To assess the efficacy and safety of hypotensive anesthesia (HA) combined with tranexamic acid (TXA) for reducing perioperative blood loss in simultaneous bilateral total hip arthroplasty (SBTHA). Methods In this retrospective cohort study, a total of 183 eligible patients (15 females and 168 males, 44.01 ± 9.29 years old) who underwent SBTHA from January 2015 to September 2020 at our medical center were enrolled for analysis. Fifty‐nine patients received standard general anesthesia (Std‐GA group), the other 85 and 39 patients received HA with an intraoperative mean arterial pressure between 70 and 80 mmHg (70–80 HA group) and below 70 mmHg (
ISSN:1757-7853
1757-7861
DOI:10.1111/os.13200