Novel poly (methyl methacrylate) grafted guar gum/mineral substituted apatite nanocomposites for orthopedics applications: In vitro physicochemical and biochemical studies

A poly (methyl methacrylate) grafted guar gum/mineral substituted hydroxyapatite (PMMA-GG/M-HA) nanocomposite is reported to show enhanced physico-chemical and bio-chemical properties. This nanocomposite offers a possible bone cell integration around it with augmenting fresh bone development, thus d...

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Bibliographic Details
Published in:Journal of science. Advanced materials and devices 2018-09, Vol.3 (3), p.317-322
Main Authors: Priya, G., Vijayakumari, N., Sangeetha, R.
Format: Article
Language:English
Subjects:
Bacterial activity
Guar gum
Nanocomposite
Osteoblast cell adhesion
Poly (methyl methacrylate)
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Summary:A poly (methyl methacrylate) grafted guar gum/mineral substituted hydroxyapatite (PMMA-GG/M-HA) nanocomposite is reported to show enhanced physico-chemical and bio-chemical properties. This nanocomposite offers a possible bone cell integration around it with augmenting fresh bone development, thus declining the risk of cartilages' structural collapse. In this study, the as-fabricated nanocomposite was characterized by using physicochemical strategies. The cell-material boundary of the nanocomposite was observed in vitro with human osteoblast cells, and the cell replication was tested. The nanocomposite promoted the bone cell adhesion and proliferation, improved the mechanical strength and repressed the growth of bacterial cells.
ISSN:2468-2179
2468-2179
DOI:10.1016/j.jsamd.2018.06.002