Beneficial Effects of Vitamin K Status on Glycemic Regulation and Diabetes Mellitus: A Mini-Review

Type 2 diabetes mellitus is a chronic disease that is characterized by hyperglycemia, insulin resistance, and dysfunctional insulin secretion. Glycemic control remains a crucial contributor to the progression of type 2 diabetes mellitus as well as the prevention or delay in the onset of diabetes-rel...

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Bibliographic Details
Published in:Nutrients 2020-08, Vol.12 (8), p.2485
Main Authors: Ho, Hsin-Jung, Komai, Michio, Shirakawa, Hitoshi
Format: Article
Language:English
Subjects:
Adult
Aged
Biomarkers
Calcification
Clinical trials
Complications
Diabetes
Diabetes Complications - prevention & control
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - metabolism
Diabetes Mellitus, Type 2 - prevention & control
Dietary Supplements
Disease Progression
Female
Glucagon
Glucose
Glycemic Control
glycemic status
Health risks
Humans
Hyperglycemia
Insulin
Insulin Resistance
Insulin secretion
insulin sensitivity
Kidneys
Liver
Male
Metabolism
Middle Aged
Nutritional Status
Pancreas
Peptides
Phylloquinone
Physiology
Plasma
Proteins
Review
Sensitivity
Vitamin K
Vitamin K - administration & dosage
Vitamin K - pharmacology
Vitamin K - physiology
Women
Young Adult
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Description
Summary:Type 2 diabetes mellitus is a chronic disease that is characterized by hyperglycemia, insulin resistance, and dysfunctional insulin secretion. Glycemic control remains a crucial contributor to the progression of type 2 diabetes mellitus as well as the prevention or delay in the onset of diabetes-related complications. Vitamin K is a fat-soluble vitamin that plays an important role in the regulation of the glycemic status. Supplementation of vitamin K may reduce the risk of diabetes mellitus and improve insulin sensitivity. This mini-review summarizes the recent insights into the beneficial effects of vitamin K and its possible mechanism of action on insulin sensitivity and glycemic status, thereby suppressing the progression of diabetes mellitus.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu12082485