P-97 THE ROLE OF PSYCHOLOGICAL STRESS IN METABOLIC DYSFUNCTION ASSOCIATED STEATOTIC LIVER DISEASE. A PILOT STUDY

No Metabolic dysfunction associated steatotic liver disease (MASLD) pathogenesis is multifactorial. Increasing evidence highlight the role of psychosocial stress in liver disease progression. However, psychological characteristics involved in stress response in MASLD has not been investigated. Objec...

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Published in:Annals of hepatology 2024-12, Vol.29, p.101711
Main Authors: Franco, Larissa Aleman, Sandoval, Paula Gonzalez, Zúñiga, Mauro Rojas, López, Nicolas Ortiz, Buteler, Maximo Cattaneo, Cum, Juan Pablo Roblero, Teller, Jaime Poniachik, Muñoz, Caroll J Beltrán
Format: Article
Language:English
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Summary:No Metabolic dysfunction associated steatotic liver disease (MASLD) pathogenesis is multifactorial. Increasing evidence highlight the role of psychosocial stress in liver disease progression. However, psychological characteristics involved in stress response in MASLD has not been investigated. Objective: To assess psychosocial stress and its relationship with liver damage in patients with MASLD. A transversal, descriptive study, was performed in MASLD patients diagnosed by liver biopsy recruited from Gastroenterology Unit of HCUCH.Demographic and clinical data was recorded using RedCap platform. Psychological assessment was performed by questionnaires: Perceived Stress Scale-14 (PSS-14), Anxiety-Depression Survey (HADS), Coping Strategy Inventory (CSI), Quality of Life (QoL SF-36), and Hexaco-60. Liver function and liver damage was evaluated by blood test and imaging (echography, Fibroscan and magnetic nuclear resonance) respectively. Statistical analysis including t-test and chi-squared, were performed using GraphPad Prisma. Significance set at p
ISSN:1665-2681
DOI:10.1016/j.aohep.2024.101711