Nail Folds Capillaries Abnormalities Associated With Type 2 Diabetes Mellitus Progression and Correlation With Diabetic Retinopathy

Background: Diabetic retinopathy (DR) is an important microvascular consequence of long-term type 2 diabetes mellitus (T2DM), and it can lead to blindness if not properly diagnosed and managed. Nailfold video capillaroscopy (NVC) is a non-invasive technique for observing capillary microvasculature....

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Published in:Clinical medicine insights. Endocrinology and diabetes 2022-09, Vol.15, p.11795514221122828-11795514221122828
Main Authors: Abd EL-Khalik, Dina M, Hafez, Eman A, Hassan, Hanan E, Mahmoud, Asmaa E, Ashour, Doaa Maamoun, Morshedy, Nashwa A
Format: Article
Language:English
Subjects:
Blood vessels
Diabetes
Diabetic retinopathy
Edema
Nails (Anatomy)
Original Research
Pathophysiology
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Summary:Background: Diabetic retinopathy (DR) is an important microvascular consequence of long-term type 2 diabetes mellitus (T2DM), and it can lead to blindness if not properly diagnosed and managed. Nailfold video capillaroscopy (NVC) is a non-invasive technique for observing capillary microvasculature. Aim: We aimed to evaluate the nail folds capillaroscopic alterations in patients with T2DM by NVC and correlated the results to DR, and their relation to disease duration and hemoglobin A1c (HbA1c). Methods: This cross-sectional study enrolled 62 cases with T2DM (as per the American Diabetes Association criteria). All patients were subjected to NVC and ophthalmological assessment. Results: NVC revealed that Patients with DR showed significantly higher frequencies of tortuous capillaries, branched capillaries and precapillary edema versus non-DR patients with P 
ISSN:1179-5514
1179-5514
DOI:10.1177/11795514221122828