A Web-Based Cognitive Behavioral Therapy, Mindfulness Meditation, and Yoga Intervention for Posttraumatic Stress Disorder: Single-Arm Experimental Clinical Trial

Posttraumatic stress disorder (PTSD) is a debilitating, undertreated condition. The web-based delivery of cognitive behavioral therapy supplemented with mindfulness meditation and yoga is a viable treatment that emphasizes self-directed daily practice. This study aims to examine the effectiveness of...

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Bibliographic Details
Published in:JMIR mental health 2022-02, Vol.9 (2), p.e26479-e26479
Main Authors: Kirk, Megan A, Taha, Bilal, Dang, Kevin, McCague, Hugh, Hatzinakos, Dimitrios, Katz, Joel, Ritvo, Paul
Format: Article
Language:English
Subjects:
Anxiety
Behavior modification
Clinical significance
Clinical trials
Cognitive behavioral therapy
Cognitive therapy
Comorbidity
Emotions
Hypotheses
Intervention
Laboratories
Meditation
Mental depression
Mental disorders
Mental health
Mindfulness
Nervous system
Original Paper
Pain
Physiology
Post traumatic stress disorder
Psychologists
Quantitative psychology
Yoga
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Summary:Posttraumatic stress disorder (PTSD) is a debilitating, undertreated condition. The web-based delivery of cognitive behavioral therapy supplemented with mindfulness meditation and yoga is a viable treatment that emphasizes self-directed daily practice. This study aims to examine the effectiveness of a web-based cognitive behavioral therapy, mindfulness, and yoga (CBT-MY) program designed for daily use. We conducted an 8-week, single-arm, experimental, registered clinical trial on adults reporting PTSD symptoms (n=22; aged 18-35 years). Each participant received web-based CBT-MY content and an hour of web-based counseling each week. Pre-post outcomes included self-reported PTSD symptom severity, depression, anxiety, chronic pain, and mindfulness. Pre-post psychophysiological outcomes included peak pupil dilation (PPD) and heart rate variability (HRV). HRV and PPD were also compared with cross-sectional data from a non-PTSD comparison group without a history of clinical mental health diagnoses and CBT-MY exposure (n=46). Pre-post intention-to-treat analyses revealed substantial improvements in PTSD severity (d=1.60), depression (d=0.83), anxiety (d=0.99), and mindfulness (d=0.88). Linear multilevel mixed models demonstrated a significant pre-post reduction in PPD (B=-0.06; SE=0.01; P
ISSN:2368-7959
2368-7959
DOI:10.2196/26479