Left ventricular thrombus in the multisystem inflammatory syndrome in children associated with COVID-19

A 3-year-old girl presenting with fever, mucocutaneous inflammation, and acute gastrointestinal symptoms met criteria for the multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C). Echocardiography showed severely decreased left ventricular (LV) function with an apical mass....

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Bibliographic Details
Published in:Annals of pediatric cardiology 2022-01, Vol.15 (1), p.90-93
Main Authors: Barfuss, Spencer, Truong, Dongngan, James, Karen, Inman, Christi, Husain, S, Williams, Richard, Minich, L, Mart, Christopher
Format: Article
Language:English
Subjects:
Blood clot
Blood clots
Case Report
COVID-19
left ventricular thrombus
Multisystem inflammatory syndrome in children
Pediatrics
severe acute respiratory syndrome coronavirus 2
surgery
Thrombosis
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Summary:A 3-year-old girl presenting with fever, mucocutaneous inflammation, and acute gastrointestinal symptoms met criteria for the multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C). Echocardiography showed severely decreased left ventricular (LV) function with an apical mass. After treatment with intravenous (IV) immunoglobulin, IV steroids, anakinra, milrinone, and systemic anticoagulation, her LV function rapidly improved and the mass became increasingly mobile. Given the risk of systemic embolization, the mass was excised through left ventriculotomy and pathology confirmed a thrombus.
ISSN:0974-2069
0974-5149
DOI:10.4103/apc.apc_82_21