Association of exposure to environmental vanadium and manganese with lung function among young children: A population-based study

Exposure to environmental metals has been associated with health outcomes including respiratory health. Little is known about the impact of exposure to environmental metals on lung function among young children in general population. This study aimed to investigate the associations of exposure to me...

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Bibliographic Details
Published in:Ecotoxicology and environmental safety 2023-10, Vol.264, p.115430-115430, Article 115430
Main Authors: Fan, Nai-Chia, Huang, Hsin-Yi, Wang, Shih-Ling, Tseng, Yu-Lun, Chang-Chien, Ju, Tsai, Hui-Ju, Yao, Tsung-Chieh
Format: Article
Language:English
Subjects:
Children
Environmental tobacco smoke
Lung function
Manganese
Metal
Vanadium
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Summary:Exposure to environmental metals has been associated with health outcomes including respiratory health. Little is known about the impact of exposure to environmental metals on lung function among young children in general population. This study aimed to investigate the associations of exposure to metals with lung function among young children in a population-based cohort. A total of 1488 children aged 5–8 years attended a follow-up visit as part of the Longitudinal Investigation of Global Health in Taiwanese Schoolchildren (LIGHTS) cohort. We measured urinary samples of vanadium (median: 1.21 ng/mL; interquartile range (IQR): 0.73–1.98), manganese (median: 0.23 ng/mL; IQR: 0.13–0.47), arsenic (median: 40.51 ng/mL; IQR: 21.66–70.49), nickel (median: 1.09 ng/mL; IQR: 0.31–3.60), and cadmium (median: 0.26 ng/mL; IQR: 0.11–0.43) and performed lung function tests. Urinary vanadium concentrations were inversely associated with FVC (β coefficient for the highest quartile versus the other quartiles: −33.40, p = 0.001), FEV1 (β: −41.31, p 
ISSN:0147-6513
1090-2414
DOI:10.1016/j.ecoenv.2023.115430