Comparison of Trace Elements in High-Molecular-Mass Multiprotein Complex and in Female Milk from Which It Was Obtained

Background. Many biological processes are performed by different protein complexes. During the association of proteins and enzymes forming specific complexes, the latter can include ions of various metal ions, which may be important for their formation and biological function. Objective of the Studi...

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Bibliographic Details
Published in:TheScientificWorld 2019, Vol.2019 (2019), p.1-11
Main Authors: Soboleva, Svetlana E., Nevinsky, Georgy A., Zaksas, Natalia P.
Format: Article
Language:English
Subjects:
Aluminum
Analysis
Animals
Barium
Biochemistry
Biological activity
Breast milk
Breastfeeding & lactation
Cadmium
Calcium
Chemical reactions
Chromium
Coordination compounds
Copper
Emission analysis
Enzymes
Ethylenediaminetetraacetic acid
Female
Gel filtration
Ions
Iron
Lead
Magnesium compounds
Manganese
Metal ions
Metals
Metals - analysis
Milk
Milk - chemistry
Molecular Weight
Multiprotein Complexes - metabolism
Nickel
Powder
Protein binding
Proteins
Scattering, Radiation
Scientific imaging
Spectrometry
Strontium
Time Factors
Trace elements
Trace Elements - analysis
Zinc
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Summary:Background. Many biological processes are performed by different protein complexes. During the association of proteins and enzymes forming specific complexes, the latter can include ions of various metal ions, which may be important for their formation and biological function. Objective of the Studies. However, to date in the literature there are no data on metal ions that are part of any protein complexes. Methods. A very stable multiprotein complex (~1000±100 kDa) was separated from other proteins of nine samples of female milk by gel filtration on Sepharose 4B. The content of microelements in the stable multiprotein complex and milk was analyzed using two-jet plasma atomic emission spectrometry. Results. The content of different elements in milk on average decreased in the order: Ca>P>Mg>Al≥Zn≥Fe>Cu >B (0.76–3500 μg/g of dry milk powder), while the content of some elements was very low (Sr>Mn>Cr>Ba>Pb>Ag>Ni>Cd,
ISSN:2356-6140
1537-744X
1537-744X
DOI:10.1155/2019/2578975