Prevalence of Potential Pathogenic and Antimicrobial Resistant Escherichia coli in Danish Broilers

Avian pathogenic (APEC) are important bacteria in broiler production in terms of economy, welfare, and use of antibiotics. During a previous outbreak of APEC in the Nordic countries, it was suggested that the pathogenic clones of causing the outbreak originated from grandparent stock and were transm...

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Bibliographic Details
Published in:Antibiotics (Basel) 2023-02, Vol.12 (2), p.344
Main Authors: Poulsen, Louise Ladefoged, Bisgaard, Magne, Christensen, Henrik
Format: Article
Language:English
Subjects:
Ampicillin
Antibiotics
Antimicrobial agents
Antimicrobial resistance
APEC
Biosecurity
broiler breeders
broilers
Coliforms
Drug resistance
E coli
Escherichia coli
Genes
Grandparents
Hygiene
Infections
Offspring
Outbreaks
Poultry
Virulence
virulence-associated genes
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Summary:Avian pathogenic (APEC) are important bacteria in broiler production in terms of economy, welfare, and use of antibiotics. During a previous outbreak of APEC in the Nordic countries, it was suggested that the pathogenic clones of causing the outbreak originated from grandparent stock and were transmitted to the offspring, causing increased first week mortality. This study investigated whether the pathogenic potential of at the parent and broiler level differs in relation to pathogenic potential described by the level of virulence-associated genes and pattern of antimicrobial resistance. The hypothesis was that, due to higher biosecurity at the parent level, the population will show a lower level of antimicrobial resistance and carry fewer virulence-associated genes, as a result of fewer infections observed. From four parent flocks and eight broiler flocks, 715 were isolated from cloacal swabs of newly hatched chickens (Ross 308). The isolated were characterized by eight virulence-associated genes and phenotypic resistance against six antimicrobials. It was found that the prevalence of virulence-associated genes and phenotypic antimicrobial resistance varied significantly between flocks, and the virulence-associated genes and and resistance against ampicillin were significantly more prevalent in breeder flocks compared to broiler flocks.
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics12020344