Minimally invasive photoacoustic imaging: Current status and future perspectives

Photoacoustic imaging (PAI) is an emerging biomedical imaging modality that is based on optical absorption contrast, capable of revealing distinct spectroscopic signatures of tissue at high spatial resolution and large imaging depths. However, clinical applications of conventional non-invasive PAI s...

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Bibliographic Details
Published in:Photoacoustics (Munich) 2019-12, Vol.16, p.100146-100146, Article 100146
Main Authors: Zhao, Tianrui, Desjardins, Adrien E., Ourselin, Sebastien, Vercauteren, Tom, Xia, Wenfeng
Format: Article
Language:English
Subjects:
Interventional photoacoustic imaging
Minimally invasive procedures
Multi-modal imaging
Photoacoustic computed tomography
Photoacoustic endoscopy
Photoacoustic imaging
Photoacoustic microscopy
Review
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Summary:Photoacoustic imaging (PAI) is an emerging biomedical imaging modality that is based on optical absorption contrast, capable of revealing distinct spectroscopic signatures of tissue at high spatial resolution and large imaging depths. However, clinical applications of conventional non-invasive PAI systems have been restricted to examinations of tissues at depths less than a few cm due to strong light attenuation. Minimally invasive photoacoustic imaging (miPAI) has greatly extended the landscape of PAI by delivering excitation light within tissue through miniature fibre-optic probes. In the past decade, various miPAI systems have been developed with demonstrated applicability in several clinical fields. In this article, we present an overview of the current status of miPAI and our thoughts on future perspectives.
ISSN:2213-5979
2213-5979
DOI:10.1016/j.pacs.2019.100146