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Low Vitamin D Levels Are Associated with Increased Cardiac Iron Uptake in Beta-Thalassemia Major

We evaluated the association of vitamin D and parathormone (PTH) levels with cardiac iron and function in beta-thalassemia major (β-TM) patients. Two-hundred and seventy-eight TM patients (39.04 ± 8.58 years, 56.8% females) underwent magnetic resonance imaging for the assessment of iron overload (T2...

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Published in:Diagnostics (Basel) 2023-12, Vol.13 (24), p.3656
Main Authors: Meloni, Antonella, Pistoia, Laura, Vassalle, Cristina, Spasiano, Anna, Fotzi, Ilaria, Bagnato, Sergio, Putti, Maria Caterina, Cossu, Antonella, Massei, Francesco, Giovangrossi, Piera, Maffei, Silvia, Positano, Vincenzo, Cademartiri, Filippo
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Language:English
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Summary:We evaluated the association of vitamin D and parathormone (PTH) levels with cardiac iron and function in beta-thalassemia major (β-TM) patients. Two-hundred and seventy-eight TM patients (39.04 ± 8.58 years, 56.8% females) underwent magnetic resonance imaging for the assessment of iron overload (T2* technique), biventricular function parameters (cine images), and replacement myocardial fibrosis (late gadolinium enhancement technique). Vitamin D levels were deficient (
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics13243656