Prevalence and risk factors for Toxoplasma gondii infection among pregnant and postpartum women attended at public healthcare facilities in the City of Niterói, State of Rio de Janeiro, Brazil

Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated wit...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical 2013-02, Vol.46 (2), p.200-207
Main Authors: Fernanda Loureiro de Moura, Maria Regina Reis Amendoeira, Otílio Machado Pereira Bastos, Danuza Pinheiro Bastos Garcia de Mattos, Ana Beatriz Monteiro Fonseca, José Leonardo Nicolau, Leandro Baptista das Neves, Patricia Riddell Millar
Format: Article
Language:English
Subjects:
Postpartum women
Pregnant women
Seroprevalence
Toxoplasma gondii
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Summary:Introduction To determine the prevalence of immunoglobulin G (IgG) and immunoglobulin M (IgM) anti-Toxoplasma gondii antibodies among pregnant and postpartum women attended within the public healthcare system in Niterói, State of Rio de Janeiro, and to detect possible exposure factors associated with T. gondii infection in this population. Methods IgM and IgG anti-T. gondii antibodies were investigated in 276 pregnant and 124 postpartum women by using the indirect immunofluorescence (IFAT) and immunoenzymatic assay (ELISA) techniques. The participants were selected by convenience sampling. All these 400 patients filled out a free and informed consent statement, answered an epidemiological questionnaire and were informed about the disease. Results Among the 400 samples analyzed, 234 (58.5%) were reactive to IgG anti-T. gondii antibodies, according to the IFAT and/or ELISA assay. One pregnant woman was found to be reactive to IgM anti-T. gondii antibodies, with an intermediate IgG avidity test. Risk factor analysis showed that seropositivity was significantly associated (p
ISSN:0037-8682
1678-9849